Skip to content
CV Rocket
Get started
How it worksThe enginePricingBlogContactSign in

Open nowPosted 7 hours ago

Principal Research Scientist I, In Vivo CAR-T Biology

AbbVie1,756 open roles

Where
South San Francisco, CA, United States
Work mode
On site
Get the CV for this job

From $25 per CV, paid once. No subscription.

Your applicationOpen nowPrincipal Research Scientist I, In Vivo CAR-T BiologyAbbVie · South San Francisco, CA, United States

  1. YouYes, apply to this one.

  2. CV RocketCV written for this posting.

  3. 25 readersRecruiter, hiring manager, skeptic. Round after round.

  4. CV RocketApplied on AbbVie's own form.

The reply lands in your private mailbox

3×more interviews than doing it yourself with ChatGPT.

The clock on this job

Early applications get read.

12.8% of postings close within 7 days. Measured by our own scanner across the market. AbbVie postings stay open a median of 31 days.

Share of postings closed within
  1. 2.2%1 day
  2. 4.5%3 days
  3. 12.8%7 days
  4. 20.6%14 days
  5. 35.6%30 days
  6. 58.4%60 days
This job: posted 7 hours ago

AbbVie median: 31 days open

The posting

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

AbbVie is seeking an accomplished in vitro preclinical scientist to join the in vivo CAR Biology group as a Principal Research Scientist I. This individual will play a significant role in integrating emerging platform capabilities with novel CAR-T designs and discovery projects to advance next-generation in vivo CAR T-cell therapies from concept through IND-enabling studies.

Responsibilities:

  • Function as a Principal Investigator within the in vivo CAR Biology in vitro preclinical team by defining original scientific hypotheses and research and development strategies for novel in vivo CAR T-cell therapies.
  • Anticipate and critically evaluate scientific advances or competitive threats and respond with appropriate new research proposals.
  • Collaborate with Quantitative Medicine, Biotherapeutics, Genetic Medicine, and Discovery Research mRNA-tLNP groups to design and functionally test novel CAR constructs that address key therapeutic challenges.
  • Lead laboratory project execution by translating therapeutic hypotheses into actionable plans; defining integrated timelines, milestones, dependencies, deliverables, and ownership; ensuring adherence and accountability; and partnering with workstream authors to flag schedule risks and implement mitigation plans.
  • Represent project teams by providing stakeholders with clear, timely updates on scientific strategy, experimental progress, key decisions, and project risks.
  • Mentor/supervise a team of one or more and evaluate the performance of those individuals; is accountable for the effective performance of the team/individuals.
  • Demonstrate creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals.
  • Primary author of novel workflows, publications, presentations, regulatory documents and/or primary inventor of patents.
  • Present research findings and innovative ideas at leading scientific conferences to strengthen AbbVie’s scientific reputation and engagement with external stakeholders and collaborators.

Qualifications

  • BS or equivalent education with typically 14+ years of experience; MS or equivalent education with typically 12+ years of experience; or PhD with typically 6+ years of experience in CAR-T discovery research, cell therapy, or immuno-oncology.
  • Expertise in designing, generating, and preclinically evaluating CAR-T candidates; experience developing next-generation in vivo lentiviral CAR-T platforms is strongly preferred.
  • Expertise in synthetic biology, T-cell biology, and immuno-oncology applied to CAR design and next-generation in vivo CAR-T platform innovation.
  • Experience developing complex, semi-automated experimental and analytical workflows and functional screening assays to improve the throughput, reproducibility, and efficiency of CAR-T candidate discovery, characterization, and selection.
  • Demonstrated capacity to function as a Principal Investigator by generating original technical ideas, defining research or development strategies, and leading multidisciplinary teams through execution and scientific decision-making.
  • Exceptional project management and prioritization skills, with demonstrated ability to define integrated research timelines, manage dependencies and competing priorities, establish clear ownership, hold contributors accountable, and proactively communicate and mitigate delivery risks.
  • Demonstrated success as a primary author of publications, presentations, or regulatory documents and/or as a primary inventor on patents, with a record of communicating complex scientific findings effectively to internal and external audiences.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

  • The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​
  • We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​
  • This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

From $25, paid onceGet the CV for this job

What happens when you press

One press. We do the rest.

  1. A CV for this posting

    Written against AbbVie's own wording, from every piece of relevant proof in your profile.

  2. 25 readers review it

    Recruiter, hiring manager, skeptic and more read every draft, round after round. You get the best round.

    The review screen in CV Rocket: how each CV was read, round by round.

  3. We apply on AbbVie's form

    Our application engine gets through the hardest forms there are. Where a question needs you, AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

    An application in CV Rocket: every answer filled in on the employer's form.

  4. Every reply, sorted

    AbbVie's answer lands in your private mailbox, and we classify it on arrival: interview, question, rejection.

    The CV Rocket inbox: each employer reply classified as an interview, an action or a rejection.

  5. Reply with AI

    AI helps you write the email, checks it and sends it. We show you whether the recruiter read it.

  6. The interview in your calendar

    Full integration with your calendar. The invitation goes straight in.

    An interview invitation in the CV Rocket inbox, added to the candidate's calendar.
Get the CV for this job

From $25 per CV, paid once. No subscription.

Why it works

3×

more interviews than doing it yourself with ChatGPT.

ChatGPT writes a CV and never learns what happened to it. We see every reply. For each CV we know:

  • How it was written, and how the review scored it
  • When we applied, and how long after the posting went up
  • Which posting, which company, which city
  • Who got the interview, and who heard nothing

That is how we know which CVs get called.

Get the CV for this job

From $25 per CV, paid once. No subscription.

The numbers game

More applications. More interviews.

Every application goes out with its own CV, written for that posting and paid once. Send enough of them and the law of large numbers finds you the job.

Get the CV for this job
By hand5–10
With CV Rocket100
applications a day

Nearby

Live postings like this one

Same employer first, then the same role elsewhere.

Before you press

Straight answers

Get the CV for this job

From $25 per CV, paid once. No subscription.

What if my background isn't good enough?

We make the most of the background you have. The CV uses every piece of relevant proof your profile holds, and one of the 25 readers reads your whole profile and flags what the CV left out.

Do you really apply for me?

Yes, on the employer's own form, the hardest ones included. Where a question needs you, you answer it right there and AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

Is it a subscription?

No. You pay once per CV, from $25. Every application goes out with its own CV, written for that posting.

One job. One CV.
Paid once.

Pick the posting you want. We write for it, apply for you and catch the reply.

Get the CV for this job

From $25 per CV, paid once. No subscription.