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Open nowPosted today

Senior Biotechnologist (Upstream Processing)

ANTER CONSULTING PTE. LTD.

Pay
SGD 4,500 – SGD 6,200 a month
Where
Singapore
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Your applicationOpen nowSenior Biotechnologist (Upstream Processing)ANTER CONSULTING PTE. LTD. · Singapore
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This job: posted today

The posting

A global life sciences company in Singapore is looking for a Senior Biotechnologist to join its upstream processing team on a major new vaccine programme. You will join during equipment commissioning and start-up, then carry that knowledge into routine manufacturing as the facility transitions to operations. This is a non-shift role with standard office hours.

Key Responsibilities

  • Support commissioning and qualification of upstream equipment such as fermenters, bioreactors, centrifuges, media preparation and seed train systems
  • Participate in FAT, SAT, walkdowns and punch list closure, and support IQ/OQ execution as user representative
  • Take part in water runs, engineering runs, demonstration batches and PPQ batches, including in-process sampling and data collection
  • Draft, review and revise batch records, work instructions and SOPs for new upstream unit operations
  • Build, test and review MES recipes and electronic work instructions for accuracy, operability and GMP compliance
  • Execute upstream manufacturing to schedule: media preparation, seed train, fermentation, harvest and centrifugation
  • Operate and monitor process equipment and automation systems, and troubleshoot process and equipment issues
  • Raise and lead deviation investigations and support CAPA and change control
  • Drive continuous improvement in cycle time, yield and right-first-time performance
  • Act as subject matter expert for assigned unit operations, train and coach junior biotechnologists, and deputise for the shift lead as required
  • Support project-to-operations handover and audit and inspection readiness

Requirements

  • Degree or Diploma in Biotechnology, Bioprocess Engineering, Chemical Engineering, Life Sciences or a related discipline
  • Minimum 3 years in GMP biopharmaceutical or vaccine manufacturing, with substantial hands-on upstream experience
  • Experience in fermentation or cell culture, centrifugation, harvest and related upstream unit operations
  • Direct involvement in equipment commissioning, qualification or facility start-up, including water runs or engineering runs
  • Practical MES experience, such as authoring, reviewing or testing electronic batch records
  • Experience drafting and revising batch records, SOPs and work instructions
  • Strong knowledge of GMP, good documentation practice and data integrity
  • Experience leading deviation investigations and supporting CAPA and change control
  • Able to train junior team members and deputise for a shift lead
  • Willing to support extended hours during commissioning and validation campaigns

Preferred

  • Vaccine manufacturing background, especially recombinant or microbial-derived products
  • Greenfield or brownfield facility start-up experience through to commercial production
  • Experience with DeltaV, Siemens PCS7 or a similar DCS
  • New MES deployment experience from configuration to GMP release
  • Tech transfer or NPI exposure, and regulatory inspection support

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