The posting
Sr. Bioprocess Associate
About Astellas
Astellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.
Are you driven to make a real difference in the lives of patients?
We're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.
Purpose & Scope
The Senior Associate, Technical Development Operations will participate in upstream and downstream areas of AAV development and production within process development and the pilot plant for gene therapy programs and processes. This position is in South San Francisco, CA.
Role and Responsibilities
- Perform all operations as directed per internal policies and other requirements.
- Perform legible, clear, and concise data entry into batch records, logbooks, and all other ancillary controlled forms used in the process
- Maintain a high level of attention to detail with regards to all aspects of process execution
- Operate production equipment, including inspection, set up, processing, and cleaning
- Execute corrective measures addressing any issues in a timely manner
- Attend safety meetings and follow all safety procedures as defined, including maintaining a safe work environment for both self and colleagues. Execute corrective measures addressing any issues in a timely manner
- Ability to contribute to process improvement plans and help drive to completion
- Conduct operations in a collaborative, team environment with a positive attitude to accomplish goals
- Available to work outside of normal business hours and/or overtime as required
- Execute process development experiments following defined experimental plans
- Oversee and execute production of non-clinical material
- Assist in the evaluation and incorporation of new technologies
- Other duties as assigned
Required Qualifications
- Bachelor's degree with 5+ years lab experience or Master's degree with 3+ years lab experience.
- Exhibit proficiency with upstream and/or downstream bioprocessing unit operations (i.e., Cell Culture, Harvest, Tangential Flow Filtration, Column Chromatography)
- Working experience in the development of SOPs or batch records.
- Ability to maintain accurate records and effectively manage multiple projects
- Ability to work productively in a collaborative and cross functional team environment with internal and external partners across multiple scientific disciplines
- Excellent organizational, written, and oral communication skills to convey technical information clearly to diverse audiences.
- Strong communicator with ability to work effectively both independently and as part of a team
- Demonstrated experience in maintaining detailed records and ability to assist in document revisions
- Strong computer skills including MS Office (Word, Excel, PowerPoint)
- Effective problem-solving skills
- Available to work outside of normal business hours and/or weekends as required
Preferred Qualifications
- Experience in process development of cell culture and/or protein purification processes
- Experience working with viruses, especially Adeno-Associated Virus (AAV)
- Experience working in biotech and pharma
- Technical understanding of a biotech manufacturing facility
- Experience with single-use technologies
- Ability to multi-task, be flexible and to thrive in a fast-paced environment, as well as the capacity to handle uncertainty and changing priorities
Location and Working Environment
- This position is based in South San Francisco and will require on-site work.
What awaits you at Astellas?
- Global collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide. Real-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.
- Relentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.
- A Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.
Our Organizational Values and Behaviors
Values: Innovation, Integrity and Impact sit at the heart of what we do.
Behaviors: We come together as ‘One Astellas’, working with courage and a sense of urgency. We are outcome focused and consistently take accountability for our personal contribution.
Salary Range
$82,880 – $118,400 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations)
Benefits:
- Medical, Dental and Vision Insurance
- Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
- 401(k) match and annual company contribution
- Company paid life insurance
- Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
- Long Term Incentive Plan for eligible positions
- Company fleet vehicle for eligible positions
- Referral bonus program
#LI-TR1
