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Open nowPosted 6 days ago

Principal Scientist, Translational Science Immunology

CSL74 open roles

Where
Americas, US-MA, Waltham, CSL Behring
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Your applicationOpen nowPrincipal Scientist, Translational Science ImmunologyCSL · Americas, US-MA, Waltham, CSL Behring

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The clock on this job

Early applications get read.

8.1% of postings close within 7 days. Measured by our own scanner across the market. CSL postings stay open a median of 4 days.

Share of postings closed within
  1. 1.8%1 day
  2. 3.6%3 days
  3. 8.1%7 days
  4. 15.1%14 days
  5. 33.9%30 days
This job: posted 6 days ago

CSL median: 4 days open

The posting

CSL Behring is a global biopharmaceutical leader committed to developing innovative therapies for patients with rare and serious diseases. Our Immunology franchise is advancing a diverse pipeline targeting autoimmune and inflammatory conditions across rheumatology, neuroimmunology, and rare dermatology.

Could you be our next Principal Scientist, Translational Science Immunology? The job is in our Waltham MA Office. This is a hybrid position three days a week onsite. You will report to the Senior Director, Translational Research.

You will be responsible for leading and executing translational research and preclinical development activities in relation to the Research Projects to support the Immunology Therapeutic Area Portfolio. You will focus on design, planning, execution, and reporting of Work-Packages related to Pharmacology and Translational Research. The incumbent fosters innovation and maintains CSL’s scientific leadership. The role includes collaborating with lab staff and CROs, representing the Translational Research team internally and externally, and contributing to strategic initiatives through collaboration, scientific excellence, and project delivery.

RESPONSIBILITIES AND ACCOUNTABILITIES:

1 Design and implement in vitro and ex vivo studies to investigate the mechanism of action of lead therapeutic candidates, understand disease patho-mechanisms and drive target validation activities.

2 Design appropriate PD response/biomarker strategies and assays to support non-GLP/GLP toxicology studies and first in human clinical studies/early clinical studies, including writing Biomarker Strategy Documents and leading Biomarker Expert Teams.

3 Collaborate with Immunology focused In vivo pharmacology researchers to provide pre-clinical studies in support of indication selection, including writing project proposals, research plans, and research agreements.

4 Collaborate with clinical researchers/clinical development team (lead clinicians, clinical pharmacology, clinical biomarkers) to provide pre-clinical studies to support indication selection and biomarker strategy, including writing project proposals, research plans, human ethics applications and research agreements.

5 Contribute to writing investigator brochures, regulatory submission, clinical study reports and other documents to support project progression

6 Works with Research Therapeutic Area Lead (RTAL) to develop and implement Research Strategy and to ensure project planning and execution is aligned with TA priorities.

7 Effectively liaises between Research TA Core team and Translational Research team together with key internal functions regarding strategic priorities and project implementation.

8 Provides Research input into early phase NPO due diligence process.

9 Works to build external scientific and industry networks relevant to Immunology TA (working with relevant members of Senior Management in Research function)

Experience:

  • PhD in discipline relevant to Immunology TA (Immunology, Cellular Biology)
  • 10+ years academic and / or industry experience relevant to Immunology TA
  • Immunology or immune-mediated disease(s)Track record in the development and conduct of high-quality research activity relevant to Immunology or immune-mediated disease(s)
  • Experience in translation of research outcomes into early clinical development

The expected base salary range for this position at hiring is $145,000 - $180,000. Please note this salary range reflects the minimum and maximum base pay that CSL expects to pay for this position at the time of this posting in MA. Individual base salary for a successful candidate is determined by qualifications, skill level, experience, competencies and other relevant factors. In addition to base salary, total compensation for this role may also include incentive compensation and equity.

About CSL Behring

CSL Behring is a global biotherapeutics leader driven by our promise to save lives. Focused on serving patients’ needs by using the latest technologies, we discover, develop and deliver innovative therapies for people living with conditions in the immunology, hematology, cardiovascular and metabolic, respiratory, and transplant therapeutic areas. We use three strategic scientific platforms of plasma fractionation, recombinant protein technology, and cell and gene therapy to support continued innovation and continually refine ways in which products can address unmet medical needs and help patients lead full lives.

CSL Behring operates one of the world’s largest plasma collection networks, CSL Plasma. Our parent company, CSL, headquartered in Melbourne, Australia, employs 32,000 people, and delivers its lifesaving therapies to people in more than 100 countries.

To learn more about CSL, CSL Behring, CSL Seqirus and CSL Vifor visit https://www.csl.com/ and CSL Plasma at https://www.cslplasma.com/.

Our Benefits

For more information on CSL benefits visit How CSL Supports Your Well-being | CSL.

You Belong at CSL

At CSL, Inclusion and Belonging is at the core of our mission and who we are. It fuels our innovation day in and day out. By celebrating our differences and creating a culture of curiosity and empathy, we are able to better understand and connect with our patients and donors, foster strong relationships with our stakeholders, and sustain a diverse workforce that will move our company and industry into the future.

To learn more about inclusion and belonging visit https://www.csl.com/careers/inclusion-and-belonging

Equal Opportunity Employer

CSL is an Equal Opportunity Employer. If you are an individual with a disability and need a reasonable accommodation for any part of the application process, please visit https://www.csl.com/accessibility-statement.

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