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Senior Scientist

Cytokinetics79 open roles

Where
South San Francisco, California
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Your applicationOpen nowSenior ScientistCytokinetics · South San Francisco, California
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The clock on this job

Early applications get read.

12.1% of postings close within 7 days. Measured by our own scanner across the market. Cytokinetics postings stay open a median of 42 days.

Share of postings closed within
  1. 2.1%1 day
  2. 4.5%3 days
  3. 12.1%7 days
  4. 19.1%14 days
  5. 35.6%30 days
  6. 52.7%60 days
This job: posted yesterday

Cytokinetics median: 42 days open

The posting

Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.

We welcome exceptional individuals to join us in our mission to develop potential medicines to improve the health span of people with cardiovascular diseases of impaired muscle function. We are seeking a highly skilled and motivated Analytical Chemist with expertise in analytical development and laboratory studies. The ideal candidate is an experienced analytical professional with proven track records in laboratory studies, Analytical Development, Quality Control, and technical support to Drug Substance and Drug Product manufacturing processes. This position offers an exciting opportunity to contribute to the development of novel therapeutics, support the launch of a new commercial product, and to work in a dynamic and collaborative cross functional team environment.

Job purpose

We are seeking a highly motivated and hands-on Senior Scientist, Analytical Development, to support in-house analytical development activities across Cytokinetics' small molecule pipeline. This laboratory-based role will be responsible for designing and executing analytical studies to support drug substance and drug product development from early-stage research through clinical development. The successful candidate will apply scientific expertise in chromatographic, spectroscopic, and physicochemical characterization techniques to solve technical challenges, generate high-quality data, and support critical development decisions. Working closely with Process Chemistry, Pharmaceutical Development, DMPK, Manufacturing, and Quality functions, this individual will contribute to analytical method development, product characterization, investigation activities, and continuous improvement initiatives in a collaborative team environment.

Responsibilities

  • Design, execute, and document analytical studies supporting drug substance and drug product development. Develop, optimize, qualify, and troubleshoot analytical methods used for release, stability, characterization, and process support testing.
  • Perform hands-on laboratory testing using chromatographic, spectroscopic, and physicochemical analytical techniques.
  • Characterize drug substances, intermediates, degradation products, excipients, and drug products to support development programs.
  • Generate, analyze, interpret, and present scientific data to support development decisions and project milestones.
  • Collaborate with Process Chemistry, Formulation Development, DMPK, Pharmacology, and Manufacturing teams to address analytical and technical challenges.
  • Support analytical investigations associated with atypical results, laboratory events, and method performance issues.
  • Maintain laboratory instruments and equipment, including calibration, qualification, troubleshooting, and routine maintenance activities.
  • Prepare and review analytical protocols, study reports, technical summaries, and laboratory documentation.
  • Support analytical method transfers, validation activities, specification development, and stability studies as needed.
  • Contribute to laboratory operational excellence through process improvements, scientific innovation, and knowledge sharing. Ensure laboratory activities are conducted in accordance with applicable procedures, quality standards, and regulatory expectations.
  • Strive for a collaborative, innovative, and results-oriented analytical development culture.
  • undefined

Qualifications

  • BS/MS in Analytical Chemistry, Chemistry, Pharmaceutical Sciences, or a related discipline; PhD preferred but not required.
  • 5+ years of pharmaceutical industry experience in analytical development, quality control, or related analytical laboratory environments.
  • Strong hands-on experience with analytical characterization of small molecule drug substances and drug products.
  • Demonstrated expertise with HPLC/UHPLC and other analytical techniques such as LC-MS, GC, dissolution, Karl Fischer titration, XRPD, DSC/TGA, particle size analysis, and related instrumentation.
  • Experience developing, optimizing, qualifying, and troubleshooting analytical methods.
  • Strong laboratory skills with the ability to independently design experiments, interpret results, and solve technical problems.
  • Familiarity with cGMP requirements and pharmaceutical development practices.
  • Excellent technical writing and documentation skills.
  • Strong communication and collaboration skills with the ability to work effectively in cross-functional teams.
  • Ability to manage multiple priorities in a dynamic and fast-paced development environment. #LI-ONSITE

Pay Range:

The expected salary range for this position based on the primary location of South San Francisco, CA is $162,000 - $189,000. The base pay offered will take into account internal equity and may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Base salary is just one component of our competitive total compensation package, which includes equity in the form of stock options and/or restricted stock units, comprehensive health, dental, vision, life and disability insurance coverage, 401k retirement benefits with employer match, learning and wellness stipends, and paid time off. Note that benefits are subject to change and may vary based on jurisdiction of employment.

Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.

Please review our General Data Protection Regulation (GDPR) policy PRIOR to applying.

Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do – all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves.

Fraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers

Recently, there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain (Cytokinetics.com) and will only be made after completing a formal interview process.

Here are some ways to check for authenticity:

  • We do not conduct job interviews through non-standard text messaging applications
  • We will never request personal information such as banking details until after an official offer has been accepted and verified
  • We will never request that you purchase equipment or other items when interviewing or hiring
  • If you are unsure about the authenticity of an offer, or if you receive any suspicious communication, please contact us directly at [email protected]

Please visit our website at: www.cytokinetics.com

Cytokinetics is an Equal Opportunity Employer

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