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PhD Position in Understanding Cellular Mechanisms Driving Traumatic Brain Injury-Associated Dementia Are you passionate about uncovering what happens to the brain during impact, subsequent injury, and how the injury evolves, or resolves, afterwards? Then we are inviting you to join our interdisciplinary research teams to explore the long-term effects of repetitive mild traumatic brain injury (rmTBI) in both humans and mouse models. PhD Position in Understanding Cellular Mechanisms Driving Traumatic Brain Injury-Associated Dementia Are you passionate about uncovering what happens to the brain during impact, subsequent injury, and how the injury evolves, or resolves, afterwards? Then we are inviting you to join our interdisciplinary research teams to explore the long-term effects of repetitive mild traumatic brain injury (rmTBI) in both humans and mouse models. PhD Position in Understanding Cellular Mechanisms Driving Traumatic Brain Injury-Associated Dementia Repeated mild head injuries, the kind sustained by athletes, veterans, and victims of domestic violence, are increasingly linked to long-term memory problems and a higher risk of dementia later in life. Strikingly, these lasting effects can occur even when no visible brain damage is present. Yet, we still don't understand how repeated injury leads to memory decline, and there are currently no treatments that address these long-term cognitive consequences. In this project, our main goal is to dissect the molecular and cellular mechanisms underlying traumatic brain injury (TBI)-associated neurodegeneration, memory decline and dementia. To this end we will study how rmTBI triggers long-term neuroinflammation and cellular and functional changes in the hippocampus, leading to memory impairment, as TBI may weaken the brain's resilience, accelerating hippocampus-related memory decline. This project is a collaboration between the Fitzsimons lab at the Swammerdam Institute for Li...



