Skip to content
CV Rocket
Get started
How it worksThe enginePricingBlogContactSign in

Open nowPosted 16 days agoWe saw it 100 min after it went up

Scientist I, Synthetic Biology

Generate Biomedicines23 open roles

Pay
$102,000 – $130,000 a year
Where
Somerville, MA
Get the CV for this job

From $25 per CV, paid once. No subscription.

Your applicationOpen nowScientist I, Synthetic BiologyGenerate Biomedicines · Somerville, MA

  1. YouYes, apply to this one.

  2. CV RocketCV written for this posting.

  3. 25 readersRecruiter, hiring manager, skeptic. Round after round.

  4. CV RocketApplied on Generate Biomedicines's own form.

The reply lands in your private mailbox

3×more interviews than doing it yourself with ChatGPT.

The clock on this job

Early applications get read.

12.9% of postings close within 7 days. Measured by our own scanner across the market. Generate Biomedicines postings stay open a median of 24 days.

Share of postings closed within
  1. 2.2%1 day
  2. 4.7%3 days
  3. 12.9%7 days
  4. 21.0%14 days
  5. 35.6%30 days
  6. 58.5%60 days
This job: posted 16 days ago

Generate Biomedicines median: 24 days open

The posting

The Role:

Generate’s Prototyping Lab builds the experimental systems that let us measure protein function at unprecedented scale. By combining synthetic biology, large DNA libraries, high-throughput assays, and machine learning, the team creates workflows that turn complex biological questions into rich, usable datasets.

We’re looking for two Scientists with a strong record in experimental synthetic biology to develop pooled screens capable of testing hundreds of thousands of protein variants in parallel to identify protein binders and modulators. You’ll shape these experiments via DNA library design, pooled in vitro protein display, and NGS-based enrichment analysis. For one of the two roles, we are looking for a Scientist who additionally has experience in mammalian cell engineering and membrane protein studies. Experience in computational modeling or statistical analysis would help you connect experimental design to the quality and usefulness of the resulting data.

You’ll work closely with Protein Sciences and Machine Learning teams to build screening approaches that deliver clear, quantitative insight into protein function. The role offers substantial scope to originate and advance new technologies, with close collaboration across a well-resourced biotech team.

Here's how you will contribute:

  • Build pooled screening workflows to achieve scalable protein binding and functional readouts, from assay setup through data interpretation.
  • Collaboratively establish reliable assay conditions, quantitative measures, and handoff plans that enable project teams to maximize platform utility.
  • Identify opportunities to test unconventional hypotheses, applying the strongest concepts for drug program acceleration and supporting IP filings.
  • Synthesize findings into clear recommendations, and present them in presentations and in writing to colleagues across disciplines.
  • Use quantitative reasoning, modeling, and critical literature review to inform experimental choices.

The Ideal Candidate will have:

  • PhD in synthetic or systems biology, bioengineering or a related field with 0-1 year of experience; alternatively, a bachelor’s or master’s degree with at least 6 years of highly relevant experience.
  • Hands-on experience designing and running pooled binding screens, ideally using both purified proteins and cell-based assays.
  • For one of the roles, we are seeking strong cell-culture skills, including experience engineering cell lines for screening applications using methods such as CRISPR, lentiviral transduction, or transposon-based integration; experience working with membrane proteins is also highly preferred.
  • Experience designing and building pooled DNA libraries, and using next-generation sequencing to track enrichment in selection campaigns.
  • Familiarity with recombinant protein production, purification, and/or binding assays is an advantage.
  • Ability to interpret complex screening data and write scripts in Python or a similar language; familiarity with AI-assisted coding tools such as Cursor or other LLM-based platforms.
  • Applies quantitative reasoning and sound experimental judgment to assess data quality, troubleshoot assays, and guide next steps.
  • Takes ownership of applied biology projects from initial concept through execution, analysis, and delivery.
  • Brings intellectual curiosity to new technical challenges, shares expertise readily, and helps colleagues grow through collaboration and mentorship.
  • High level of cross-functional autonomy and self-motivation.

Who will love this job:

  • Biologists who integrate computational insight with experimentation to tackle complex problems.
  • Experimentalists who enjoy making difficult targets, including membrane proteins, tractable for pooled binding screens.
  • Platform builders who value assay robustness, data quality, and interpretable results alongside throughput.

#LI-HM1

About Generate Biomedicines

We are a clinical-stage generative biology company pioneering the AI revolution in drug design and development. We are advancing a new approach to drug creation—one grounded in the ability to design proteins with defined biological intent. By integrating machine learning with large-scale experimentation, this approach aims to reduce the uncertainty, time, and cost associated with developing protein-based medicines.

Founded in 2018, we are advancing a growing pipeline of clinical and preclinical programs across multiple disease areas and protein modalities. By unifying computational design and clinical development within a single operating model, we translate this approach into clinical-stage programs and are leading a shift from traditional drug discovery toward systematic drug generation.

At Generate:Biomedicines, we collaborate across disciplines in new ways to invent and innovate. We bring diverse perspectives to a shared goal of delivering better medicines to patients in need, faster, guided by our values and leadership behaviors.

Generate:Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies: Generate:Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate:Biomedicines or its employees is strictly prohibited unless contacted directly by the Company’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate:Biomedicines and the Company will not owe any referral or other fees with respect thereto.

Compensation: The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package.

Per Year Salary Range

$102,000—$130,000 USD

From $25, paid onceGet the CV for this job

What happens when you press

One press. We do the rest.

  1. A CV for this posting

    Written against Generate Biomedicines's own wording, from every piece of relevant proof in your profile.

  2. 25 readers review it

    Recruiter, hiring manager, skeptic and more read every draft, round after round. You get the best round.

    The review screen in CV Rocket: how each CV was read, round by round.

  3. We apply on Generate Biomedicines's form

    Our application engine gets through the hardest forms there are. Where a question needs you, AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

    An application in CV Rocket: every answer filled in on the employer's form.

  4. Every reply, sorted

    Generate Biomedicines's answer lands in your private mailbox, and we classify it on arrival: interview, question, rejection.

    The CV Rocket inbox: each employer reply classified as an interview, an action or a rejection.

  5. Reply with AI

    AI helps you write the email, checks it and sends it. We show you whether the recruiter read it.

  6. The interview in your calendar

    Full integration with your calendar. The invitation goes straight in.

    An interview invitation in the CV Rocket inbox, added to the candidate's calendar.
Get the CV for this job

From $25 per CV, paid once. No subscription.

Why it works

3×

more interviews than doing it yourself with ChatGPT.

ChatGPT writes a CV and never learns what happened to it. We see every reply. For each CV we know:

  • How it was written, and how the review scored it
  • When we applied, and how long after the posting went up
  • Which posting, which company, which city
  • Who got the interview, and who heard nothing

That is how we know which CVs get called.

Get the CV for this job

From $25 per CV, paid once. No subscription.

The numbers game

More applications. More interviews.

Every application goes out with its own CV, written for that posting and paid once. Send enough of them and the law of large numbers finds you the job.

Get the CV for this job
By hand5–10
With CV Rocket100
applications a day

Nearby

Live postings like this one

Same employer first, then the same role elsewhere.

Before you press

Straight answers

Get the CV for this job

From $25 per CV, paid once. No subscription.

What if my background isn't good enough?

We make the most of the background you have. The CV uses every piece of relevant proof your profile holds, and one of the 25 readers reads your whole profile and flags what the CV left out.

Do you really apply for me?

Yes, on the employer's own form, the hardest ones included. Where a question needs you, you answer it right there and AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

Is it a subscription?

No. You pay once per CV, from $25. Every application goes out with its own CV, written for that posting.

One job. One CV.
Paid once.

Pick the posting you want. We write for it, apply for you and catch the reply.

Get the CV for this job

From $25 per CV, paid once. No subscription.