Skip to content
CV Rocket
Get started
How it worksThe enginePricingBlogContactSign in

Open nowPosted 23 hours ago

Sr. Manager - IT

Genetix Biotherapeutics14 open roles

Pay
$170,000 – $185,000 a year
Where
Somerville, MA
Get the CV for this job

From $25 per CV, paid once. No subscription.

Your applicationOpen nowSr. Manager - ITGenetix Biotherapeutics · Somerville, MA

  1. YouYes, apply to this one.

  2. CV RocketCV written for this posting.

  3. 25 readersRecruiter, hiring manager, skeptic. Round after round.

  4. CV RocketApplied on Genetix Biotherapeutics's own form.

The reply lands in your private mailbox

3×more interviews than doing it yourself with ChatGPT.

The clock on this job

Early applications get read.

12.3% of postings close within 7 days. Measured by our own scanner across the market. Genetix Biotherapeutics postings stay open a median of 45 days.

Share of postings closed within
  1. 2.1%1 day
  2. 4.5%3 days
  3. 12.3%7 days
  4. 19.7%14 days
  5. 35.6%30 days
  6. 58.0%60 days
This job: posted 23 hours ago

Genetix Biotherapeutics median: 45 days open

The posting

About Genetix Biotherapeutics

At Genetix Biotherapeutics every role has meaning, every team member is respected, and every day is a chance to make a difference. When you join Genetix, you're not just landing a new role, you become part of a company that's pursuing curative gene therapies to give patients and their families more days. We are doers, thinkers and collaborators who embrace and live by our values:

Our innovation is rooted in the diversity of our teams and results are achieved through cooperation and the integration of multiple viewpoints. This is personal and we approach every challenge with radical care.

This role is based in Somerville, MA and follows a hybrid schedule of three days onsite per week.

To support regular in-office collaboration, only candidates within commuting distance of Somerville will be considered.

Position Summary

The Senior Manager, IT owns the day-to-day delivery of the security and infrastructure services that support Genetix’s commercial products. You will lead identity, endpoint, backup and recovery, network, and cloud operations during a period of active modernization, including a move of identity services toward Microsoft Entra, a rebuild of backup and DR, and hardening of both corporate and laboratory environments. This is a hands-on leader who can run projects through change control in a validated, regulated environment, manage vendors, and build a team and operating rhythm that is secure, auditable, and reliable.

RESPONSIBILITIES

Identity & Access

  • Lead identity modernization across Microsoft Entra ID, Okta, and hybrid Active Directory, including SSO migrations for business applications, conditional access, MFA coverage, and authentication policy.
  • Own privileged access: PIM, admin role reduction, service account de-privileging and lifecycle (inventory, owner, expiry, rotation), and stale account cleanup.
  • Run access governance and least-privilege role design for business applications, with timely provisioning and deprovisioning for employees, contractors, consultants, and managed service providers.
  • Own the AD security backlog, directory sync health (Entra Connect), and Group Policy migration to Intune.

Infrastructure, Backup & Cloud

  • Operate core infrastructure: AWS (multi-account, federated access, networking), on-prem and virtualized servers, firewalls and VPN, and legacy file services.
  • Build and run backup and recovery, including backup platform deployment, network paths to cloud targets, restore testing, retention, and data archiving.
  • Lead patching and lifecycle: OS and application patching, server and client end-of-life, and scheduled outage coordination.
  • Manage DNS and domain hygiene, including verification records, decommissioned records, and legacy domain consolidation, to reduce attack surface.
  • Lead monitoring and observability, including tool replacement and alerting tied to incident response.

Endpoint, Lab & Security Operations

  • Own endpoint and lab security: disk encryption and Secure Boot compliance, endpoint management, DNS-layer protection, patch policy for lab and corporate systems, and removal of retired tools.
  • Own intake and triage of security reports, including phishing submissions and external vulnerability disclosures, with defined response and closure.
  • Support audits and customer or partner security assessments (GxP, 21 CFR Part 11, SOX, SOC 2), including questionnaires, evidence collection, and remediation tracking.

Validated Systems & Change Control

  • Partner with Quality and application owners on infrastructure for validated systems (LIMS/ELN, statistical computing, lab instruments), including server builds, security hot fixes, non-production testing, regression sign-off, and change control.
  • Support commercial and partner-facing systems and treatment center security and connectivity requirements.

Team, Vendors & Delivery

  • Lead, coach, and develop engineers and analysts; set priorities and manage workload across projects and service requests.
  • Manage managed service providers and vendors (SLAs, contracts, performance, escalation).
  • Define SLAs and reporting for security and infrastructure requests, and improve intake, approval, and onboarding workflows with the service desk.
  • Write runbooks, SOPs, and change records so operations are repeatable and audit-ready.
  • Apply AI tools such as Claude in daily work, including integrations with enterprise systems, and champion responsible AI adoption with appropriate access controls.

QUALIFICATIONS

Required

  • Bachelor’s degree in IT, Computer Science, Information Security, or a related field, or equivalent practical experience.
  • 8+ years in IT infrastructure, security operations, or systems engineering, including 3+ years leading people or technical teams.
  • Hands-on identity experience: Entra ID and hybrid Active Directory required; Okta or another SSO platform strongly preferred. Includes conditional access, MFA, PIM, and service account governance.
  • Hands-on experience with endpoint management (Intune), disk encryption, patching, and vulnerability management.
  • Experience with backup and recovery platforms, cloud networking (AWS preferred), firewalls and VPN, and Microsoft 365.
  • Experience managing projects through formal change control and managing vendors.
  • Experience supporting audits or compliance programs in a regulated environment.
  • Working knowledge of AI tools such as Claude (or similar) applied to operations.
  • Strong communication skills, risk-based decision making, and the ability to prioritize competing demands in a small, fast-moving team.

Preferred

  • Biotech, pharma, or GxP experience, including computer system validation and supporting lab systems and instrumentation.
  • Experience modernizing hybrid environments (IdP migrations, GPO to Intune, monitoring replacement, legacy domain consolidation).
  • Security or infrastructure certifications (e.g., CISSP, CISM, Security+, AWS Security Specialty, Microsoft identity/security certifications).
  • Experience in a company that is rebuilding or scaling its IT function.

Additional Information

The pay transparency range provided below is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. We may ultimately pay more or less than the posted range, and the range may be modified in the future. This role is eligible for an annual bonus and long-term incentive. Actual base salary pay will be based on several factors, including but not limited to experience, skills, relevant education/qualifications, external market, internal equity, and other job-related factors permitted by law.

Genetix’s total rewards package also provides employees with a comprehensive and competitive benefits suite to support a variety of employee needs. These benefits include comprehensive health, life and disability insurance, employer-matched 401(k) plan, lifestyle spending account, flexible time-off + paid holidays and winter holiday period, tuition reimbursement & loan repayment assistance, paid parental leave, paid onsite parking, commuter subsidy, and much more.

Pay Transparency

$170,000—$185,000 USD

Genetix is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics.

From $25, paid onceGet the CV for this job

What happens when you press

One press. We do the rest.

  1. A CV for this posting

    Written against Genetix Biotherapeutics's own wording, from every piece of relevant proof in your profile.

  2. 25 readers review it

    Recruiter, hiring manager, skeptic and more read every draft, round after round. You get the best round.

    The review screen in CV Rocket: how each CV was read, round by round.

  3. We apply on Genetix Biotherapeutics's form

    Our application engine gets through the hardest forms there are. Where a question needs you, AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

    An application in CV Rocket: every answer filled in on the employer's form.

  4. Every reply, sorted

    Genetix Biotherapeutics's answer lands in your private mailbox, and we classify it on arrival: interview, question, rejection.

    The CV Rocket inbox: each employer reply classified as an interview, an action or a rejection.

  5. Reply with AI

    AI helps you write the email, checks it and sends it. We show you whether the recruiter read it.

  6. The interview in your calendar

    Full integration with your calendar. The invitation goes straight in.

    An interview invitation in the CV Rocket inbox, added to the candidate's calendar.
Get the CV for this job

From $25 per CV, paid once. No subscription.

Why it works

3×

more interviews than doing it yourself with ChatGPT.

ChatGPT writes a CV and never learns what happened to it. We see every reply. For each CV we know:

  • How it was written, and how the review scored it
  • When we applied, and how long after the posting went up
  • Which posting, which company, which city
  • Who got the interview, and who heard nothing

That is how we know which CVs get called.

Get the CV for this job

From $25 per CV, paid once. No subscription.

The numbers game

More applications. More interviews.

Every application goes out with its own CV, written for that posting and paid once. Send enough of them and the law of large numbers finds you the job.

Get the CV for this job
By hand5–10
With CV Rocket100
applications a day

Nearby

Live postings like this one

Same employer first, then the same role elsewhere.

Before you press

Straight answers

Get the CV for this job

From $25 per CV, paid once. No subscription.

What if my background isn't good enough?

We make the most of the background you have. The CV uses every piece of relevant proof your profile holds, and one of the 25 readers reads your whole profile and flags what the CV left out.

Do you really apply for me?

Yes, on the employer's own form, the hardest ones included. Where a question needs you, you answer it right there and AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

Is it a subscription?

No. You pay once per CV, from $25. Every application goes out with its own CV, written for that posting.

One job. One CV.
Paid once.

Pick the posting you want. We write for it, apply for you and catch the reply.

Get the CV for this job

From $25 per CV, paid once. No subscription.