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Open nowPosted 9 hours ago

Senior Contracts Manager, Clinical Agreements

Kardigan35 open roles

Pay
$153,000 – $199,000 a year
Where
Princeton, New Jersey, United States
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Your applicationOpen nowSenior Contracts Manager, Clinical AgreementsKardigan · Princeton, New Jersey, United States

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The clock on this job

Early applications get read.

7.9% of postings close within 7 days. Measured by our own scanner across the market. Kardigan postings stay open a median of 26 days.

Share of postings closed within
  1. 1.6%1 day
  2. 3.4%3 days
  3. 7.9%7 days
  4. 14.2%14 days
  5. 34.1%30 days
This job: posted 9 hours ago

Kardigan median: 26 days open

The posting

About Us

Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.

It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.

Led by Tassos Gianakakos, Jay Edelberg, M.D., Ph.D., and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.

We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.

At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. Driven by patients and their families, we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in being authentic—leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an eagerness to learn, we encourage the highest levels of curiosity and are open to changing our minds. We are committed to winning as a team with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to enable the impossible because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.

These values are the foundation of our work, empowering us to make a real difference, every day.

Position Title: Senior Contracts Manager

Department: Legal

Reports To: Vice President, Corporate Law and Head of Transactions

Location: Princeton, NJ – On-site 4 days per week (Mon to Thurs)

Job Overview

Kardigan is seeking an experienced Senior Contracts Manager to lead the negotiation and management of Clinical Trial Agreements and other clinical-related agreements in support of Kardigan’s clinical development programs. This is a hands-on drafting and negotiation role — the primary focus is clinical contracting, with additional responsibility for general contracting needs across the business as they arise. This role does not have ownership of Kardigan’s contract lifecycle management (CLM) system implementation or administration, which is led separately within the Legal team. Kardigan seeks an exceptional candidate with strong clinical contracts experience who can collaborate cross-functionally, negotiate agreements independently, and communicate clearly and effectively with stakeholders at all levels. Attention to detail is essential. You will join our fast-paced legal team, reporting to our Vice President, Corporate Law and Head of Transactions, and will interface directly with Clinical Operations, R&D, and other business stakeholders across the company.

Essential Duties and Responsibilities

Clinical Contracting (Primary Responsibility)

  • Independently draft, review, and negotiate Clinical Trial Agreements (US and ROW), Local Sponsor Agreements, and CRO agreements.
  • Draft and negotiate clinical-adjacent agreements including Data Sharing and Data Processing Agreements, Standard Contractual Clauses (GDPR), Informed Consent Forms, Early Access/Compassionate Use Program agreements, Pharmacy Agreements, Indemnification Agreements, and Letters of Authorization/POAs.
  • Serve as the primary contracts point of contact for Clinical Operations, working closely with the team to troubleshoot obstacles that arise during clinical trial start-up, site activation, and ongoing conduct.
  • Track key clinical contract obligations, milestones, renewals, and deadlines across active studies and sites.
  • Build and maintain effective working relationships with clinical sites, CROs, CMOs, investigators, and other external clinical stakeholders.
  • Stay current on clinical trial regulatory and industry requirements (e.g., GCP, ICH) as they affect contract terms.

General Contracting

  • Draft, review, and negotiate additional company contracts as needed, including vendor and supplier agreements, MSAs, SOWs/WOs, consulting agreements, and NDAs.
  • Translate business needs into clear, legally sound contract language that balances risk mitigation with operational flexibility.
  • Serve as a resource to internal stakeholders — including Legal, Procurement, R&D, Finance, and IT — on contracting matters outside the clinical space.
  • Use Kardigan’s CLM system (Agiloft) for contract intake, drafting, routing, and tracking; partner with the Legal team members responsible for CLM administration on process and workflow questions, without owning system implementation or administration.

Risk Management & Compliance

  • Identify, assess, and escalate legal and business risks in a timely manner.
  • Ensure contractual terms comply with applicable laws, company policies, and industry regulations.
  • Monitor contract-related activities for compliance with internal policies and applicable law.

Business Partnership

  • Serve as a trusted advisor and liaison to Clinical Operations and other functions on contract negotiation strategy, process, and status.
  • Communicate contract status, priorities, and risks clearly to stakeholders at all levels.
  • Partner with the broader Legal team on cross-functional initiatives and process improvements affecting clinical and general contracting.

General

  • Support special projects and other contract-related initiatives as needed.
  • Perform other duties as requested

Qualifications and Preferred Skills

  • Bachelor’s degree preferred; paralegal certification a plus.
  • At least 7–10 years of relevant contracts experience, with substantial, hands-on experience drafting and negotiating Clinical Trial Agreements and related clinical agreements within the pharmaceutical, biotech, or life sciences industry.
  • Proven track record negotiating CRO and vendor agreements, data privacy agreements (GDPR/Standard Contractual Clauses), and reviewing Informed Consent Forms.
  • Working knowledge of the clinical trial regulatory framework (e.g., GCP, ICH) as it relates to contracting.
  • Comfortable also handling general commercial contracts (vendor, consulting, NDA, MSA/SOW) outside the clinical space.
  • Experience with contract lifecycle management systems, e-signature platforms (e.g., DocuSign), and collaboration tools; prior experience with Agiloft a plus.
  • Strong organizational and planning skills, with the ability to triage, prioritize, and manage multiple concurrent negotiations in a fast-paced environment.
  • Excellent issue-spotting, problem-solving, and communication skills, with the ability to collaborate with individuals at all levels inside and outside the organization.
  • Proficient in Microsoft Office Suite.
  • Commitment to integrity, ethical conduct, and handling confidential information with discretion.
  • Meticulous attention to detail; able to work independently with good judgment and a strong team-oriented mindset.

Exact Compensation may vary based on skills, experience and location.

Pay range

$153,000—$199,000 USD

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