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Open nowPosted 6 hours ago

Staff IT Systems Engineer, Endpoints

Lila Sciences111 open roles

Pay
$140,000 – $172,667 a year
Where
Cambridge, MA USA
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Your applicationOpen nowStaff IT Systems Engineer, EndpointsLila Sciences · Cambridge, MA USA

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The clock on this job

Early applications get read.

10.3% of postings close within 7 days. Measured by our own scanner across the market. Lila Sciences postings stay open a median of 45 days.

Share of postings closed within
  1. 2.0%1 day
  2. 4.2%3 days
  3. 10.3%7 days
  4. 15.9%14 days
  5. 34.1%30 days
This job: posted 6 hours ago

Lila Sciences median: 45 days open

The posting

Your Impact at LILA

Lila is hiring a Staff IT Systems Engineer, Endpoints to own the architecture and roadmap for endpoint management across the company. This role sits within IT & Security and supports the technology every scientist, engineer, and employee relies on, including laptops, mobile devices, specialized research compute, endpoint security, and device trust.

We treat endpoint management as a software engineering discipline. Configuration, policy, remediation, and fleet operations should move through code, CI/CD, staged rollout, observability, and automated rollback. This is a hands-on staff-level role for someone who can set technical standards, build missing tooling, mentor engineers, and lead cross-functional initiatives across IT, Security, Research Computing, and Lab Operations.

As Lila scales its workforce and physical footprint, endpoint systems need to become more automated, secure, auditable, and seamless. The right person will help employees and scientists become productive faster while reducing device risk, operational noise, and manual toil.

What You'll Be Building

  • Own the architecture and roadmap for Lila’s endpoint fleet across macOS, Windows, Linux, mobile devices, and specialized research or lab computing endpoints.
  • Define standards for endpoint configuration, policy, remediation, observability, and rollout practices across the IT & Security team.
  • Drive configuration-as-code adoption for MDM policies, profiles, scripts, staged rollouts, canary groups, and automated rollback.
  • Design zero-touch provisioning workflows so devices arrive encrypted, configured, compliant, and productive out of the box.
  • Partner with Security to integrate endpoint posture, device trust, vulnerability data, EDR, and Zero Trust access controls.
  • Build automation and internal tooling using scripts, APIs, CI/CD, and AI-assisted engineering practices to reduce manual toil.
  • Improve vulnerability and patch management through telemetry, dashboards, drift detection, and auditable compliance workflows.
  • Support specialized computing environments, including research workstations, lab-adjacent systems, VDI, managed browsers, and remote-access patterns where appropriate.
  • Serve as a technical escalation point for complex endpoint issues and mentor engineers across IT and Security.
  • Partner across Security, Legal, HR, Research Computing, and Lab Operations to protect sensitive IP while keeping the employee experience seamless.

What You'll Need to Succeed

  • Deep experience in IT systems engineering, endpoint engineering, infrastructure, or platform engineering, with staff-level technical ownership.
  • Strong experience with modern MDM or UEM platforms such as Jamf, Intune, Workspace ONE, or similar tools.
  • Experience managing endpoint configuration through code, automation, version control, staged rollout, or CI/CD practices.
  • Strong systems knowledge across macOS and Windows endpoint environments.
  • Ability to build and maintain automation using Python, Bash, PowerShell, APIs, or similar tooling.
  • Experience using AI-assisted engineering, LLM APIs, internal copilots, or agentic automation to reduce operational toil in IT, endpoint, infrastructure, or platform operations.
  • Experience partnering with Security on endpoint hardening, device trust, vulnerability management, EDR, or Zero Trust initiatives.
  • Strong troubleshooting ability across endpoint, identity, network, application, and user-experience boundaries.
  • Track record mentoring engineers, setting technical standards, and leading cross-functional technical initiatives.
  • Clear written and verbal communication skills with the ability to influence technical decisions across teams.

Bonus Points For

  • Experience supporting scientific, research, lab, OT, or high-performance computing environments.
  • Familiarity with Okta, SAML, SCIM, device trust, SASE, EDR, or cloud access patterns.
  • Experience with AWS, GCP, cloud-native infrastructure, or cloud-based endpoint telemetry workflows.
  • Experience with open-source endpoint tooling such as osquery, Fleet, Munki, or similar tools.
  • Experience building VDI, managed browser, call center, or contact center computing environments.
  • Proficiency in Go, Swift, or another language used for custom endpoint tooling.
  • Experience in a regulated, IP-sensitive, biotech, life-sciences, or research environment.

Compensation

We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.

U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.

International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.

Expected Base Salary Range

$140,000—$172,667 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.

LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.

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