Senior Manager, FP&A – G&A Business Partner

The posting

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way.

The Senior Manager of FP&A will be a key member of Madrigal’s Finance team, serving as both a strategic business partner and a hands-on leader of the financial planning and analysis processes supporting Madrigal’s G&A organization.

This highly visible role will serve as the strategic finance partner to numerous members of Madrigal’s Executive Leadership Team (ELT) and their respective departments, including the CFO, CIO, CHRO, CLO. The Senior Manager of FP&A will be a trusted advisor who shapes resource allocation decisions, informs investment priorities, and translates financial results into actionable insights for executive stakeholders. The ideal candidate brings strong financial acumen and progressive FP&A experience, inclusive of OpEx budgeting and forecasting, month-end close processes, and executive-level business partnering. Prior experience supporting a CIO / IT function is strongly preferred. Additionally, the candidate should have excellent presentation skills and the executive presence to lead discussions with, and influence, members of the ELT and department heads.

Key Responsibilities

• Strategic ELT Business Partnering: Serve as the strategic finance partner to numerous members of the Executive Leadership Team and their departments. Build trusted relationships with ELT members and department leaders, providing forward-looking insights into planning, forecasting, variance analysis, and investment decisions, and proactively bringing recommendations that shape strategy and resource allocation.

• Technology & IT Finance: Partner with the CIO and IT leadership on technology spend planning, including software/SaaS licensing, infrastructure, IT services, and vendor contracts, as well as capital versus expense treatment of technology investments. Evaluate business cases, ROI, and total cost of ownership for major technology initiatives, and track spend against approved budgets.

• Month End Close & Spend Governance: Own the month-end close process for G&A departments, ensuring accurate accrual, prepaid, and reclass entries in partnership with Accounting. Establish and reinforce spend governance, ensuring Purchase Orders are opened in line with approved budgets and proactively escalating unbudgeted commitments to business partners and Finance leadership.

• Budgeting and Forecasting: Lead the annual budget, quarterly forecast, and long-range planning processes for G&A departments for all OpEx spend, inclusive of headcount forecasting, as well as capital expenditures. Drive continuous improvement of planning processes, models, timelines, and stakeholder engagement.

• Financial Reporting & Executive Communication: Own monthly and quarterly financial reporting, including actual-versus-budget/forecast reporting for business partners and quarterly LBE (Latest Best Estimate) reporting. Develop and present ELT-ready materials that clearly communicate financial performance, key drivers, risks, and opportunities.

Required & Desired Qualifications

• Bachelor’s degree in accounting, finance, or related field; MBA, CPA, or CFA preferred.

• 8+ years of progressive finance/FP&A experience required, 2+ years in the pharma/biotech/life sciences industry preferred.

• Prior experience supporting a CIO / IT function strongly preferred, including technology spend planning, software and infrastructure costs, IT vendor management, and capitalization of internal-use software.

• Demonstrated track record serving as a strategic partner to executive-level leaders, with the executive presence to advise ELT members and the ability to manage multiple senior stakeholders and competing priorities.

• Expert proficiency with Excel and advanced PowerPoint skills, including the ability to build executive-ready presentations.

• Strong communication skills, both written and verbal, and a desire to collaborate with colleagues across different functions.

• Ability to collaborate cross-functionally and influence decisions at all levels of the organization, up to and including the ELT.

• Have a strong degree of self-motivation, ownership, and flexibility, and the ability to proactively plan and prioritize workload in a fast-paced environment.

• Experience with financial systems including Coupa, Concur, ERP systems (SAP, NetSuite, etc.), and consolidation systems (Datarails, Hyperion, OneStream, etc.).

• Strong understanding of US GAAP accounting, including capitalization of software and IT costs.

• Minimum requirement of 3 days in office each week.

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Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $151,214 - $177,203 per year. We comply with all applicable minimum wage laws.

All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization.

Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact [email protected].

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.

Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to [email protected].