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Open nowPosted 7 hours ago

Manufacturing Associate II, Oligo

Maravai LifeSciences12 open roles

Where
San Diego, CA
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Your applicationOpen nowManufacturing Associate II, OligoMaravai LifeSciences · San Diego, CA
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The clock on this job

Early applications get read.

8.2% of postings close within 7 days. Measured by our own scanner across the market. Maravai LifeSciences postings stay open a median of 35 days.

Share of postings closed within
  1. 1.8%1 day
  2. 3.8%3 days
  3. 8.2%7 days
  4. 15.2%14 days
  5. 34.2%30 days
This job: posted 7 hours ago

Maravai LifeSciences median: 35 days open

The posting

Who we are:

Maravai LifeSciences translates extraordinary science into everyday miracles, helping biotech, biopharma, and life sciences companies everywhere deliver novel vaccines, therapeutics, and diagnostics. We are global leaders in providing products and services within the fields of nucleic acid production and biologics safety testing to many of the world's leading biopharma, vaccine, diagnostics, and cell and gene therapy companies.

At Maravai, we believe that diverse perspectives are the foundation of innovation. Through an inclusive and equitableculture where every team member is inspired to bring their best selves to work, we cultivate an environment in which we can lead together, providing differentiated value to our customers, and enabling the miracles of science. For over 35 years, Maravai’s portfolio companies have served as a catalyst for innovative, lifesaving technology for humanity. Pioneering nucleotide research since its inception, we are now leading the way in the rapidly expanding mRNA market.

Your next role as a Miracle Maker

Maravai LifeSciences is seeking a #MiracleMaker to join our Oligo Manufacturing team as an Manufacturing Associate II, Oligo. The Manufacturing Associate II, Oligo is responsible for executing daily manufacturing operations to produce research- and clinical-grade oligonucleotide products in accordance with established procedures and quality standards. This role supports production activities within ISO-classified environments, including equipment setup, operation, cleaning, maintenance, and troubleshooting. The Manufacturing Associate II collaborates with cross-functional teams to ensure efficient production, adherence to cGMP requirements, and timely completion of manufacturing schedules. Additionally, this position provides technical guidance and training to junior manufacturing personnel while supporting continuous improvement initiatives.

How you will make an impact:

  • Review production schedules, interpret manufacturing specifications, calculate material requirements, and coordinate resources to ensure timely execution of production activities.
  • Prepare manufacturing areas, equipment, and materials for cGMP production activities, including project initiation and changeovers.
  • Execute manufacturing processes in accordance with approved standard operating procedures (SOPs), batch records, and cGMP requirements.
  • Accurately complete batch records, production logs, equipment records, and other required documentation in compliance with Good Documentation Practices (GDP).
  • Operate, maintain, and troubleshoot manufacturing equipment, perform routine preventive maintenance, and coordinate repairs as needed.
  • Author, review, revise, and execute batch records, SOPs, and other controlled manufacturing documents.
  • Train, mentor, and provide technical guidance to manufacturing personnel, ensuring adherence to established procedures, quality standards, and production timelines.
  • Support onboarding, qualification, and implementation of new manufacturing equipment and processes with minimal supervision.
  • Identify and troubleshoot manufacturing process issues, evaluate production bottlenecks, and implement continuous improvement initiatives to enhance operational efficiency and product quality.
  • Collaborate with Process Development, Quality, Engineering, and other cross-functional teams to support production requirements, process transfers, and manufacturing improvements.
  • Provide timely written and verbal updates to supervisors and cross-functional stakeholders regarding production progress, technical challenges, and operational priorities.
  • Maintain a safe, clean, and compliant manufacturing environment in accordance with established SOPs, safety requirements, and cGMP standards.
  • Complete required training within established timelines and maintain compliance with applicable company policies and regulatory requirements.
  • Perform plasmid DNA (pDNA) digestion, in vitro transcription (IVT), purification, and related manufacturing processes using specialized equipment in accordance with approved procedures.
  • Execute enzymatic reactions and purification processes, including operation of purification systems, preparation of batch documentation, and implementation of SOPs.
  • Perform gram-to-kilogram-scale chemical synthesis, including organic reactions, precipitation, salt exchange, extraction, deprotection, chromatography, fill-finish, and aliquoting of mRNA capping reagents, modified nucleoside triphosphates (NTPs), and other biotechnology raw materials.
  • Perform synthetic oligonucleotide manufacturing activities, including chemical reactions, purification, processing, and associated batch documentation.
  • Perform other functions and duties as required.

The skills and experience that you will bring:

  • Bachelor's degree in Chemistry, Biochemistry, Biology, Molecular Biology, or a related scientific discipline, or equivalent combination of education and relevant experience.
  • Minimum of 2 years of experience in a biochemistry, biotechnology, or related manufacturing laboratory environment.
  • Experience following, reviewing, and executing standard operating procedures (SOPs) and maintaining accurate manufacturing documentation.
  • Strong organizational skills, attention to detail, and demonstrated ability to troubleshoot and resolve technical issues.
  • Effective written and verbal communication skills, with the ability to collaborate across cross-functional teams.
  • Ability to work independently, manage competing priorities, and meet established production timelines.
  • Experience working in a current Good Manufacturing Practice (cGMP) environment, including ISO Class 7 or ISO Class 8 cleanrooms.
  • Experience drafting, revising, and implementing SOPs, batch records, and other controlled manufacturing documents.
  • Hands-on experience with chemical synthesis and purification processes involving mRNA capping reagents, modified nucleoside triphosphates (NTPs), or other biotechnology raw materials at scales ranging from 1 to 500 grams.
  • Familiarity with manufacturing equipment operation, troubleshooting, preventive maintenance, and process improvement initiatives.
  • Proficiency in Microsoft Office Suite, including Word, Excel, and Outlook.

The anticipated hourly rate for this position is $25 - $30 per hour. The offer will depend on multiple factors which may include the successful candidate's skills, experience and other qualifications, as well as the location of the role.

#LI-Onsite

The benefits of being a #MiracleMaker:

  • You have the potential to change, improve, and save lives around the world.
  • You have the opportunity to be a part owner in Maravai through RSU grants and optional employee stock purchase plans.
  • We offer comprehensive medical plans and HSA/FSA options.
  • Fertility & family planning assistance.
  • A variety of additional optional benefits and insurance options, including pet insurance.
  • Retirement contributions.
  • Holidays & Paid Time Off.

Benefits may vary by region and employment type and do not apply to temporary employees or contractors. See a comprehensive list of benefits at our Benefits & growth site at https://www.maravai.com/careers/benefits-and-growth/

To view more opportunities to become a #MiracleMaker, visit our career site at https://www.maravai.com/careers/

Maravai LifeSciences is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex including sexual orientation, and gender identity, national origin, disability, protected Veteran Status, or any other characteristic protected by applicable federal, state, or local law.

Click here to view Maravai LifeSciences Privacy Notice

HIRING SCAM ALERT

Recently, individuals impersonating Maravai LifeSciences Human Resources members have offered fraudulent interviews and job offers to unsuspecting candidates. To help protect you from these scam artists, please be aware that:

  • Maravai LifeSciences will never interview a candidate over RingCentral, similar messaging apps or social media (e.g. Telegram, Google Hangouts, WhatsApp, Facebook Messenger, etc.)
  • Maravai LifeSciences will never send a company check or ask an applicant to pay a fee or purchase at home work/training materials in connection with an application for employment.
  • Maravai LifeSciences will never provide excess money to an applicant and ask the applicant to write a check for repayment.

If you have any doubt about a job offer or any other communication purporting to come from Maravai LifeSciences, please reach out to us directly at [email protected]. If you believe you have been a victim of fraud, you can report this activity at: www.iC3.gov or www.stopfraud.gov.

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