Skip to content
CV Rocket
Get started
How it worksThe enginePricingBlogContactSign in

Open nowPosted 14 hours ago

Scientist I/Senior Engineer I, Pilot Lab Lead

Sail Biomedicines12 open roles

Where
Cambridge, MA
Get the CV for this job

From $25 per CV, paid once. No subscription.

Your applicationOpen nowScientist I/Senior Engineer I, Pilot Lab LeadSail Biomedicines · Cambridge, MA

  1. YouYes, apply to this one.

  2. CV RocketCV written for this posting.

  3. 25 readersRecruiter, hiring manager, skeptic. Round after round.

  4. CV RocketApplied on Sail Biomedicines's own form.

The reply lands in your private mailbox

3×more interviews than doing it yourself with ChatGPT.

The clock on this job

Early applications get read.

7.8% of postings close within 7 days. Measured by our own scanner across the market.

Share of postings closed within
  1. 1.6%1 day
  2. 3.4%3 days
  3. 7.8%7 days
  4. 14.3%14 days
  5. 33.7%30 days
This job: posted 14 hours ago

The posting

The Scientist I/Senior Engineer I, Pilot Lab lead will oversee a pilot laboratory responsible for producing engineered RNA (eRNA) and targeted lipid nanoparticles (tLNPs). A primary responsibility is the regular execution and delivery of gram-scale eRNA and/or tLNP manufacturing campaigns. This individual will manage direct reports while remaining actively involved in laboratory operations. They will create an organized, efficient, and scalable working environment; introduce and improve processes; and ensure that manufacturing activities are completed safely, consistently, on schedule, and with accurate documentation. The role requires independent judgment, strong scientific or engineering acumen, and effective cross-functional collaboration.

Key Responsibilities:

  • Plan, execute, and deliver recurring gram-scale eRNA and tLNP manufacturing campaigns for large in vivo studies.
  • Lead and participate in eRNA and/or tLNP manufacturing activities, including IVT, chromatography, T-mixer lipid formulation, conjugation or targeting operations, normal (NFF) and tangential flow filtration (TFF), and fill-finish, as applicable.
  • Manage, coach, and develop a small team of scientists and/or engineers by setting priorities, assigning work, providing technical guidance, and supporting professional development.
  • Oversee daily pilot laboratory operations, including production scheduling, capacity planning, equipment coordination, material readiness, inventory, and laboratory organization.
  • Develop, implement, optimize, and transfer scalable eRNA and tLNP processes into routine pilot-laboratory manufacturing.
  • Provide technical leadership for upstream and downstream eRNA production, including synthesis, purification, filtration, concentration, and buffer exchange.
  • Troubleshoot complex process, equipment, and manufacturing issues using scientific or engineering principles and independent judgment.
  • Identify bottlenecks and implement improvements that increase throughput, process robustness, consistency, and ease of execution.
  • Author and review protocols, batch records, SOPs, technical reports, equipment procedures, and process-development documentation, ensuring records are accurate, complete, and traceable.
  • Analyze process and analytical data, communicate recommendations, and collaborate with Process Development, Analytical Development, Research, Quality, Operations, Facilities, EHS, and in vivo study teams.
  • Promote a culture of safety, accountability, collaboration, technical rigor, and attention to detail.

Requirements for Either Level:

  • Demonstrated experience leading, supervising, or developing technical personnel.
  • Experience in biotechnology, pharmaceutical development, bioprocessing, or biologics manufacturing.
  • Hands-on experience executing pilot-scale or gram-scale manufacturing processes.
  • Experience developing, scaling, transferring, or routinely executing biological production processes.
  • Experience with relevant unit operations such as TFF, chromatography, filtration, concentration, or buffer exchange.
  • Strong technical writing, documentation, organizational, and problem-solving skills.
  • Demonstrated ability to manage competing priorities and deliver manufacturing campaigns on schedule.

Qualifications:

Scientist I

  • PhD in a relevant scientific or engineering discipline; MS with at least 6 years of relevant industry experience; or BS with at least 8 years of relevant industry experience.

Senior Engineer I

  • Master’s degree in engineering or a related discipline with at least 4 years of relevant industry experience; or BS in an engineering discipline with at least 6 years of relevant industry experience.

Preferred Qualifications:

  • Direct experience producing LNPs or tLNPs at gram scale for in vivo studies.
  • Experience with RNA or eRNA synthesis, purification, and drug-substance manufacturing.
  • Hands-on experience with T-mixer formulation and TFF process development or execution.
  • Experience operating in a pilot-scale, process-development, GLP, or GMP-adjacent environment.
  • Experience introducing new equipment or processes into an active manufacturing laboratory.

Salary Range: $100,000 - $150,000

Sail Biomedicines is an Equal Opportunity Employer. Sail does not discriminate based on race, religion, color, sex, gender identity, sexual orientation, age, national origin, veteran status, or any other status protected under federal, state, or local law.

From $25, paid onceGet the CV for this job

What happens when you press

One press. We do the rest.

  1. A CV for this posting

    Written against Sail Biomedicines's own wording, from every piece of relevant proof in your profile.

  2. 25 readers review it

    Recruiter, hiring manager, skeptic and more read every draft, round after round. You get the best round.

    The review screen in CV Rocket: how each CV was read, round by round.

  3. We apply on Sail Biomedicines's form

    Our application engine gets through the hardest forms there are. Where a question needs you, AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

    An application in CV Rocket: every answer filled in on the employer's form.

  4. Every reply, sorted

    Sail Biomedicines's answer lands in your private mailbox, and we classify it on arrival: interview, question, rejection.

    The CV Rocket inbox: each employer reply classified as an interview, an action or a rejection.

  5. Reply with AI

    AI helps you write the email, checks it and sends it. We show you whether the recruiter read it.

  6. The interview in your calendar

    Full integration with your calendar. The invitation goes straight in.

    An interview invitation in the CV Rocket inbox, added to the candidate's calendar.
Get the CV for this job

From $25 per CV, paid once. No subscription.

Why it works

3×

more interviews than doing it yourself with ChatGPT.

ChatGPT writes a CV and never learns what happened to it. We see every reply. For each CV we know:

  • How it was written, and how the review scored it
  • When we applied, and how long after the posting went up
  • Which posting, which company, which city
  • Who got the interview, and who heard nothing

That is how we know which CVs get called.

Get the CV for this job

From $25 per CV, paid once. No subscription.

The numbers game

More applications. More interviews.

Every application goes out with its own CV, written for that posting and paid once. Send enough of them and the law of large numbers finds you the job.

Get the CV for this job
By hand5–10
With CV Rocket100
applications a day

Nearby

Live postings like this one

Same employer first, then the same role elsewhere.

Before you press

Straight answers

Get the CV for this job

From $25 per CV, paid once. No subscription.

What if my background isn't good enough?

We make the most of the background you have. The CV uses every piece of relevant proof your profile holds, and one of the 25 readers reads your whole profile and flags what the CV left out.

Do you really apply for me?

Yes, on the employer's own form, the hardest ones included. Where a question needs you, you answer it right there and AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

Is it a subscription?

No. You pay once per CV, from $25. Every application goes out with its own CV, written for that posting.

One job. One CV.
Paid once.

Pick the posting you want. We write for it, apply for you and catch the reply.

Get the CV for this job

From $25 per CV, paid once. No subscription.