The posting
About Signant Health At Signant Health, we help bring life-changing treatments to patients faster. We are a global evidence generation company that supports clinical trials with smart technology, scientific expertise, and hands-on operational support — so better data leads to better decisions in healthcare. We embrace AI and advanced technologies to enhance every aspect of what we do, from data analysis to operational efficiency. Our teams work at the intersection of science, technology, and patient experience, delivering digital solutions powered by AI innovation that make clinical trials more efficient, more accurate, and more accessible around the world. Trusted by leading pharmaceutical companies and CROs, our platforms and services support studies across more than 90 countries and have contributed to hundreds of new drug approvals. If you are motivated by meaningful work, global impact, and innovation in clinical research and digital health — including the opportunity to work with cutting-edge AI technologies — you will find purpose and opportunity at Signant Health. About the Role The Lead Operations Software Engineer creates, enhances, and maintains business applications, configures custom code to support the company's business needs, and marshals those configurations through a standard SDLC progression. The Lead Engineer is responsible for project deliverables in line with quality targets and SLAs while adhering to best practices, Good Clinical Practice (GCP), the company's processes, and global industry regulations. The role requires in-depth product and user application knowledge, as well as oversight of a team of engineers within the Global Technical Delivery organization. You will be accountable for ensuring the team delivers quality projects that meet technical standards and follow software coding best practices while acting as a critical contributor to implementing and adopting the organization's initiatives and process improvements. Key Accountabilities Application Development / Study Configuration
-Oversee work from a team of engineers to ensure quality, on-time development, and release of business applications. -Set clear productivity and quality objectives for the team and track progress against development and business KPIs. -Work with management to define the vision, roadmaps, and goals, and play a key role in implementing that vision and driving process improvements. -Act as a technology and domain subject matter expert in one or more business and technical areas. -Motivate staff and strengthen teamwork. -Recommend, implement, and maintain tools associated with team-based software development while following proper documentation procedures. -Contribute to the creation of departmental procedure documents and working instructions. -Provide technical leadership to drive the successful completion of development projects. -Create and approve technical design documentation. -Assist in the creation and maintenance of technical standards. -Participate as a member of the development team to implement business applications. -Perform code reviews and enforce source control and proper coding practices. -Ensure all technical documentation is in place, reviewed, and approved for projects. -Actively participate in technical training and mentoring for junior team members and cross-functional teams. -Enforce proper JIRA etiquette, procedures across functional areas, and developer status communication to project teams. -Support all phases of verification and testing by efficiently diagnosing and resolving defects; serve as 2nd tier support for defects. -Collaborate with the Delivery Manager/Lead and Global Project Management to improve delivery time. -Understand and follow all coding standards; collaborate with the product development team to integrate implemented code and database objects into release applications; perform smoke testing for released applications as required. -Willingly adopt and support iterative process improvements set forth by GTD.
Specific to Products of IRT and Rater Station
Microsoft SQL Server Management Studio, SQL Server Reporting Services, and T-SQL. Microsoft Visual Studio IDE, ASP.NET MVC, C# with LINQ. Web code and data standards for HTML, JavaScript, XML, JSON, and REST.
Site Support Responsibilities (Rater Station only)
Adhere to source control, versioning best practices, and operational process requirements. Perform general site support in support of study configurations in the field, as required. Diagnose and resolve defects as part of general site support. Prepare and confirm all required change control documentation, including updates to design and other technical documents. Deploy resolutions to testing and production environments as required.
Quality System Responsibilities
Perform all work in accordance with documented Standard Operating Procedures (SOPs) and Working Instructions; adhere to Good Clinical Practices (GCP), 21 CFR Part 11, and other applicable regulatory requirements.
Knowledge, Skills & Attributes Essential:
Bachelor's degree in engineering, information systems, business, or computer science, or equivalent years of experience. 3–5 years of professional software development experience. Demonstrated experience providing technical leadership. Microsoft SQL Server Management Studio and T-SQL. Microsoft Visual Studio IDE, ASP.NET MVC, C# with LINQ. Web code and data standards for HTML, JavaScript, XML, JSON, and REST. Source control software such as Team Foundation Server, Bitbucket, or other Git-based tools. Strong knowledge of application development, configuration, and support areas. Ability to work independently and resourcefully toward quality, high-performance solutions. Strong problem-solving skills and sound judgment, including knowing when to escalate. Ability to provide concise and accurate feedback to clients and teams on progress and outcomes. Ability to work effectively in a team environment and provide backup support to team members. Ability to establish and maintain productive working relationships across functional areas. Strong analytical skills with a proven ability to understand business requirements and recommend improvements. Willingness to share knowledge openly, including lessons learned. Experience leading software design and development efforts on assigned projects. Experience estimating project time for quoting development and support tasks. Ability to remain calm under pressure and manage multiple tasks simultaneously. Excellent attention to detail and commitment to delivering high-quality output. Strong communication, time management, teamwork, and organizational skills.
Desirable:
Agile Scrum methodologies. Atlassian Suite tools including Bitbucket, Confluence, JIRA, X-ray, and Jira Service Manager. Microsoft SQL Server Integration Services. Microsoft SQL Server Reporting Services. Microsoft Azure, Cosmos DB, and Kubernetes. REST APIs. Familiarity with GCP and 21 CFR Part 11. Familiarity with defect tracking software. Willingness to work flexible hours.
Why Signant Health? At Signant Health, your work has real impact. Everything we build, support, and deliver helps advance clinical research and bring new treatments to patients faster — improving lives around the world. Our teams combine science, technology, and operational expertise to solve complex clinical trial challenges, and every role contributes to that mission. We offer a collaborative, global environment where you can grow your career while working alongside experts across clinical, technology, data, and operations, with opportunities to learn, take ownership, and drive meaningful innovation — not just maintain the status quo. If you are looking for purpose-driven work, smart colleagues, and the opportunity to help shape the future of clinical research and digital health, Signant Health is the place to do it. At Signant Health, accepting difference isn't enough — we celebrate it, we support it, and we nurture it for the benefit of our team members, our clients, and our community. We are proud to be an equal opportunity workplace and an affirmative action employer, committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or veteran status. Prior to their start date, all new hires are required to be verified through a thorough background check and identity verification to confirm eligibility for employment. Unsolicited resumes submitted by agencies or third-party recruiters directly to hiring managers or any Signant Health employee will not be considered and will not obligate Signant Health to any fees or terms associated with the submission.
