The posting
Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.
To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.
We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.
About the Role
What You'd Do
- Plan and deliver general anesthesia for large animal models undergoing organ procurement, long-duration perfusion procedures, and survival surgeries. This includes induction, intubation, mechanical ventilation, hemodynamic monitoring, and fluid and pharmacological support.
- Provide clinical veterinary oversight for all research animals: health assessments on arrival, quarantine and acclimation, preventive care, and diagnosis and treatment of illness.
- Direct post-operative care, analgesia, and welfare monitoring for survival surgery animals, and write the monitoring plans the vet techs carry out.
- Help build the vivarium, including SOPs, anesthesia and surgical protocols, occupational health and biosecurity practices, and staff training and competency records.
- Work with the IACUC on protocol design, amendments, and inspections, and keep the program compliant with USDA Animal Welfare Act and PHS/OLAW requirements.
- Uphold the highest standards of animal welfare, ensuring that veterinary care, perioperative management, and monitoring practices reflect current veterinary standards and ethical research principles.
- Supervise and mentor the vet tech and animal care team, and oversee OR scheduling, animal ordering, drug inventory (including controlled substances and DEA records), and equipment purchasing.
- Work with scientists and engineers to refine procurement physiology (warm ischemia, heparinization, perfusion cannulation timing) to improve organ outcomes.
About You
- DVM/VMD (or equivalent), licensed or eligible for licensure in California.
- Substantial hands-on experience with large animal welfare and anesthesia, ideally in a research or surgical setting. Porcine experience is strongly preferred.
- Experience with ventilated anesthesia, arterial and central line monitoring, and managing hemodynamically complex patients through long procedures.
- Familiarity with IACUC processes and USDA/OLAW regulations. DACLAM, DACVAA, or equivalent residency training is a strong plus.
- Experience setting up or managing an animal facility, or supervising technical staff, is a plus.
- You thrive in a startup environment, take ownership, and care about both animal welfare and scientific rigor.
As an equal opportunity employer, Until is committed to providing employment opportunities to all individuals. All applicants for positions at Until will be treated without regard to race, color, ethnicity, religion, sex, gender, gender identity and expression, sexual orientation, national origin, disability, age, marital status, veteran status, pregnancy, or any other basis prohibited by applicable law.
