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Open nowPosted 3 hours agoWe saw it 73 min after it went up

Associate Director, Quantitative System Pharmacology (QSP)

Viridian Therapeutics, Inc.2 open roles

Pay
$163,000 – $200,000 a year
Where
Waltham, MA - US
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Your applicationOpen nowAssociate Director, Quantitative System Pharmacology (QSP)Viridian Therapeutics, Inc. · Waltham, MA - US

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The clock on this job

Early applications get read.

13.5% of postings close within 7 days. Measured by our own scanner across the market. Viridian Therapeutics, Inc. postings stay open a median of 1 days.

Share of postings closed within
  1. 2.3%1 day
  2. 4.6%3 days
  3. 13.5%7 days
  4. 21.8%14 days
  5. 36.6%30 days
  6. 58.9%60 days
This job: posted 3 hours ago

Viridian Therapeutics, Inc. median: 1 days open

The posting

At Viridian, we work with a sense of urgency for patients, creating unity with our team, the industry, and the community. We are committed to using proven science and engineering to improve the lives of people living with serious and rare diseases, and we are getting closer to achieving this goal every day.

Reporting to the VP of Clinical Pharmacology & Pharmacometrics, the Associate Director, Quantitative System Pharmacology (QSP), will contribute to the Model-informed Drug Development (MIDD) strategy and execution across preclinical, translational and clinical stage programs.

This role may be based in our Waltham, MA headquarters, which would be a hybrid role, or it can also be fully remote. Our office-based employees are required to work in the office three (3) days a week. If remote, travel to headquarters for meetings would be required at the discretion of management.

Responsibilities (including, but not limited to):

  • Understand and execute the “fit-for-purpose” MIDD strategy to accelerate the program advancement
  • Experience with QSP or (m)PBPK modeling in autoimmune or inflammation for biologicals (ie, monoclonal antibodies, or other modalities), and bring forward combination drug approaches leveraging QSP models to advance clinical trials
  • Provide (semi)mechanistic modelling & simulation support and expertise to the assigned programs
  • Survey literature to gain “fit-for-purpose: understanding of preclinical and/or clinical physiological, pathological, and disease state, to enable quantitative system pharmacology modeling and simulation
  • Work in close collaboration with biologists, discovery chemistry, clinical pharmacologists, pharmacometricians and other functions to improve our understanding of disease mechanisms, modalities, and/or mono-therapy and combination therapy
  • Maintain quantitative systems pharmacology expertise in the field
  • Communicate the QSP/(m)PBPK results to across-function program team

Qualifications:

  • Requires a PhD degree or equivalent with a minimum of 6+ years of combined academic and biotechnology or pharmaceutical experience in QSP/T, (m)PBPK, mathematics, chemical/biomedical engineer, physics, and/or Translational Sciences, including experience with therapeutic antibodies
  • Demonstrated success contributing preclinical or translational, and clinical pharmacology related aspects across different stages of programs
  • Prior experience in QSP(T) with in-depth knowledge of mechanistic modelling and data interpretation, as well as track record supporting this experience
  • Independent hands-on proficiency in MATLAB/Simbiology, MoBI, GastroPlus/PK-Sim, R, or other software
  • Ability to effectively present ideas, data interpretation, for complex quantitative clinical concepts in both written and oral communication
  • Highly motivated and results-driven to deliver for corporate goals in a dynamic biotech environment
  • Demonstrated strong written and verbal communication skills
  • Proven mindset of proactive continuous improvement
  • Efficient independent worker with ability to focus and drive for results
  • Strong attention to detail
  • Ability to work in a fast-paced environment and to handle multiple tasks
  • Strong commitment to ethical standards
  • Proficient with Microsoft Office suite (i.e., Word, PowerPoint, Excel, Outlook, SharePoint, etc.)
  • The salary range for this position is commensurate with experience

Salary Range

$163,000—$200,000 USD

Viridian offers a comprehensive benefits package including:

  • Competitive pay and stock options for all employees
  • Medical, dental, and vision insurance
  • 100% Paid Parental Leave
  • Short- and long-term disability coverage
  • Life, Travel and AD&D
  • 401(k) Company Match with immediate company vest
  • Employee Stock Purchase plan
  • Generous vacation plan and paid company holiday shutdowns
  • Various fertility, mental, financial, and proactive physical health programs

Viridian Therapeutics, Inc. provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination, harassment, or retaliation of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by Federal, State, and Local laws. Viridian will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Viridian Therapeutics, Inc participates in E-Verify, the federal program for electronic verification of employment eligibility.

Applicant Privacy Notice: Information submitted in connection with your application will be processed in accordance with Viridian's Privacy Policy, available here.

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