Skip to content
CV Rocket
Get started
How it worksThe enginePricingBlogContactSign in

Open nowPosted 2 days ago

Executive Director, Commercial Analytics — Global Forecasting

vrtx293 open roles

Where
Boston, MA
Get the CV for this job

From $25 per CV, paid once. No subscription.

Your applicationOpen nowExecutive Director, Commercial Analytics — Global Forecastingvrtx · Boston, MA

  1. YouYes, apply to this one.

  2. CV RocketCV written for this posting.

  3. 25 readersRecruiter, hiring manager, skeptic. Round after round.

  4. CV RocketApplied on vrtx's own form.

The reply lands in your private mailbox

3×more interviews than doing it yourself with ChatGPT.

The clock on this job

Early applications get read.

13.9% of postings close within 7 days. Measured by our own scanner across the market. vrtx postings stay open a median of 21 days.

Share of postings closed within
  1. 2.2%1 day
  2. 4.7%3 days
  3. 13.9%7 days
  4. 22.4%14 days
  5. 38.1%30 days
  6. 59.0%60 days
This job: posted 2 days ago

vrtx median: 21 days open

The posting

Job Description

The Executive Director, Commercial Analytics — Global Forecasting will lead the integrated global forecasting capability within Global Commercial Strategy. Reporting to the Vice President, Global Commercial Analytics, this leader will be accountable for the quality, consistency, and strategic use of forecasts across the broad Vertex portfolio, spanning early pipeline, pre-launch, launch, lifecycle, and in-line products.

This is a senior enterprise leadership role with responsibility for establishing forecasting standards, governance, methodologies, and talent across the organization. The Executive Director will be a key owner of the annual Long-Range Planning (LRP) process, working closely with the Senior Vice President, Global Commercial Strategy, Corporate Finance, disease leaders, regions, and Manufacturing and Supply Chain to produce an integrated global revenue outlook and translate it into portfolio, investment, and supply-planning implications.

Key Duties & Responsibilities

  • Lead the Global Forecasting organization and capability agenda across pipeline, pre-launch, launch, lifecycle, and in-line disease areas.
  • Own the integrated global revenue outlook for the Vertex portfolio, including underlying market, patient, access, competitive, clinical, regulatory, pricing, and commercial assumptions.
  • Co-lead the annual LRP revenue forecasting process with GCS leadership and Corporate Finance, establishing the process, calendar, deliverables, governance, and executive decision points.
  • Integrate disease-area forecasts into a coherent portfolio view and clearly communicate value drivers, sensitivities, risks, opportunities, uncertainties, and implications for investment.
  • Establish enterprise forecasting standards, including model architecture, assumptions, scenario frameworks, documentation, quality control, version management, review expectations, and approval governance.
  • Create a connected forecasting model across global and regional processes, ensuring near-term in-line forecasts and longer-range global forecasts use aligned assumptions, transparent transitions, and clearly defined accountabilities.
  • Partner with Manufacturing and Supply Chain to translate commercial forecasts into demand and capacity-planning inputs, including appropriate scenarios, ranges, timing, and updates at material inflection points.
  • Ensure forecasts are refreshed when material clinical, regulatory, competitive, access, market, or supply information changes the outlook or the decisions the forecast must support.
  • Build base, upside, downside, and alternative scenarios that quantify key uncertainties and enable strategic, portfolio, launch, capital-allocation, and supply decisions.
  • Ensure forecasts integrate evidence from Market Research, Decision Science, Competitive Intelligence, epidemiology, HEOR, Value & Access, Medical, Development, and external data sources.
  • Provide objective forecasting leadership to disease teams and senior governance forums, pressure-testing assumptions and translating complex outputs into clear recommendations.
  • Establish fit-for-purpose forecasting approaches across different lifecycle stages, from early opportunity assessments and commercial due diligence through launch and mature in-line products.
  • Build scalable forecasting tools, templates, data structures, and reporting mechanisms that improve transparency, comparability, agility, and reuse across the portfolio.
  • Select and manage external forecasting partners where specialized capacity is needed while maintaining internal ownership of methodologies, assumptions, interpretation, and quality.
  • Build, develop, and retain a high-performing global forecasting team with strong technical depth, portfolio perspective, business judgment, and executive communication capability.
  • Measure forecast performance, process effectiveness, stakeholder confidence, and decision impact; use lessons learned to continuously improve models, standards, and ways of working.

Required Education Level

  • Minimum of a Bachelor’s degree in business, economics, finance, statistics, mathematics, operations research, life sciences, engineering, or a related discipline.
  • Advanced degree such as an MBA, M.S., Ph.D., or other relevant qualification preferred.

Required Experience

  • Extensive leadership experience in biopharmaceutical forecasting, commercial analytics, strategic planning, or a closely related discipline.
  • Demonstrated success leading forecasting across a broad portfolio that includes both in-line products and pipeline assets at multiple stages of development.
  • Deep expertise in global revenue forecasting, patient-based and market-based models, scenario planning, uncertainty assessment, analog selection, assumption development, and model governance.
  • Significant experience leading long-range planning and partnering with senior Commercial and Corporate Finance leaders on portfolio, investment, and enterprise planning decisions.
  • Experience integrating global, regional, and local forecasting processes and reconciling near-term operational forecasts with long-range strategic forecasts.
  • Experience partnering with Manufacturing and Supply Chain and translating commercial forecasts into demand, capacity, and supply-planning implications.
  • Experience supporting commercialization decisions across early pipeline, pre-launch, launch, lifecycle management, and established in-line businesses.
  • Demonstrated ability to establish forecasting standards, common methodologies, governance, tools, and quality controls across a complex global organization.
  • Proven success building and leading high-performing forecasting teams through senior leaders and influencing effectively in a highly matrixed environment.
  • Exceptional strategic judgment, analytical rigor, financial and commercial acumen, executive communication, and ability to constructively challenge assumptions while building alignm

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$0 - $0

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

From $25, paid onceGet the CV for this job

What happens when you press

One press. We do the rest.

  1. A CV for this posting

    Written against vrtx's own wording, from every piece of relevant proof in your profile.

  2. 25 readers review it

    Recruiter, hiring manager, skeptic and more read every draft, round after round. You get the best round.

    The review screen in CV Rocket: how each CV was read, round by round.

  3. We apply on vrtx's form

    Our application engine gets through the hardest forms there are. Where a question needs you, AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

    An application in CV Rocket: every answer filled in on the employer's form.

  4. Every reply, sorted

    vrtx's answer lands in your private mailbox, and we classify it on arrival: interview, question, rejection.

    The CV Rocket inbox: each employer reply classified as an interview, an action or a rejection.

  5. Reply with AI

    AI helps you write the email, checks it and sends it. We show you whether the recruiter read it.

  6. The interview in your calendar

    Full integration with your calendar. The invitation goes straight in.

    An interview invitation in the CV Rocket inbox, added to the candidate's calendar.
Get the CV for this job

From $25 per CV, paid once. No subscription.

Why it works

3×

more interviews than doing it yourself with ChatGPT.

ChatGPT writes a CV and never learns what happened to it. We see every reply. For each CV we know:

  • How it was written, and how the review scored it
  • When we applied, and how long after the posting went up
  • Which posting, which company, which city
  • Who got the interview, and who heard nothing

That is how we know which CVs get called.

Get the CV for this job

From $25 per CV, paid once. No subscription.

The numbers game

More applications. More interviews.

Every application goes out with its own CV, written for that posting and paid once. Send enough of them and the law of large numbers finds you the job.

Get the CV for this job
By hand5–10
With CV Rocket100
applications a day

Nearby

Live postings like this one

Same employer first, then the same role elsewhere.

Before you press

Straight answers

Get the CV for this job

From $25 per CV, paid once. No subscription.

What if my background isn't good enough?

We make the most of the background you have. The CV uses every piece of relevant proof your profile holds, and one of the 25 readers reads your whole profile and flags what the CV left out.

Do you really apply for me?

Yes, on the employer's own form, the hardest ones included. Where a question needs you, you answer it right there and AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

Is it a subscription?

No. You pay once per CV, from $25. Every application goes out with its own CV, written for that posting.

One job. One CV.
Paid once.

Pick the posting you want. We write for it, apply for you and catch the reply.

Get the CV for this job

From $25 per CV, paid once. No subscription.