Skip to content
CV Rocket
Get started
How it worksThe enginePricingBlogContactSign in

Open nowPosted yesterday

Executive Director, GCS Kidney — POVE

vrtx292 open roles

Pay
$260,600 – $390,800 a year
Where
Boston, MA
Get the CV for this job

From $25 per CV, paid once. No subscription.

Your applicationOpen nowExecutive Director, GCS Kidney — POVEvrtx · Boston, MA

  1. YouYes, apply to this one.

  2. CV RocketCV written for this posting.

  3. 25 readersRecruiter, hiring manager, skeptic. Round after round.

  4. CV RocketApplied on vrtx's own form.

The reply lands in your private mailbox

3×more interviews than doing it yourself with ChatGPT.

The clock on this job

Early applications get read.

13.6% of postings close within 7 days. Measured by our own scanner across the market. vrtx postings stay open a median of 19 days.

Share of postings closed within
  1. 2.3%1 day
  2. 4.7%3 days
  3. 13.6%7 days
  4. 21.9%14 days
  5. 36.9%30 days
  6. 59.0%60 days
This job: posted yesterday

vrtx median: 19 days open

The posting

Job Description

General Summary:

The Executive Director, Global Commercial Strategy (GCS) Kidney - Pove will be the senior commercial leader for povetacicept across the kidney indications, including immunoglobulin A nephropathy (IgAN) and primary membranous nephropathy (pMN). The role will own the global commercial strategy for the kidney franchise, supporting the near-term U.S. launch and subsequent global launches in IgAN while advancing pMN toward commercialization.

The Executive Director will co-lead the povetacicept Kidney Program Team with the Development Lead, guiding program strategy and key development, lifecycle, and investment decisions. The role will lead global launch execution and lifecycle management in IgAN and build the global commercialization and launch strategy for pMN.

Key Duties & Responsibilities

  • Co-lead the povetacicept Kidney Program Team with the Development Lead, setting the integrated strategy, priorities, and decision framework across IgAN and pMN.
  • Own the global commercial strategy for povetacicept in kidney, connecting launch, lifecycle, development, evidence, and investment priorities across the franchise.
  • Lead GCS support for the U.S. IgAN launch and subsequent global launches, ensuring clear strategy, critical success factors, regional alignment, readiness, and execution.
  • Own global lifecycle management for povetacicept in IgAN, identifying and advancing opportunities to strengthen differentiation, expand patient impact, generate evidence, and maximize long-term value.
  • Lead the global commercialization and launch strategy for pMN, including market development, positioning, target product profile, evidence needs, value proposition, launch sequencing, and readiness.
  • Shape development plans and lead commercial development activities across IgAN and pMN, including market research, forecasting, competitive intelligence, scenario planning, evidence requirements, and business cases.
  • Build deep understanding of the IgAN and pMN markets, patients, treatment pathways, competition, access dynamics, and requirements for success.
  • Ensure alignment between the kidney strategy and broader povetacicept portfolio, partnering with GCS leaders for non-kidney indications while maintaining clear accountability by vertical.
  • Partner across Development, Medical, Regulatory, Value & Access, Finance, Manufacturing, and regional Commercial teams to deliver a globally aligned strategy and launch plan.
  • Communicate clear recommendations to senior leaders and governance bodies, identifying key uncertainties, trade-offs, risks, and actions required.
  • Build and lead a high-performing kidney commercial team as the franchise advances.

Required Education Level

  • Minimum of a Bachelor’s degree in business, marketing, life sciences, healthcare, or a related field.
  • Advanced degree such as an MBA, M.S., Pharm.D., Ph.D., or M.D. preferred.

Required Experience

  • Extensive biopharmaceutical commercial experience, including global commercial strategy, new product planning, or marketing leadership.
  • Demonstrated experience leading global launch strategy and execution for specialty or rare disease products.
  • Strong experience in lifecycle management, commercial development, forecasting, evidence strategy, and investment decision-making.
  • Launch or development experience in nephrology, specialty, rare disease, immunology, or other complex markets; direct kidney experience strongly preferred.
  • Experience leading cross-functional teams in a matrixed environment; program-team leadership experience preferred.
  • Exceptional strategic thinking, analytical rigor, business judgment, communication, and influencing skills.
  • Proven people leadership and ability to build collaborative, high-performing teams.

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$260,600 - $390,800

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected]

From $25, paid onceGet the CV for this job

What happens when you press

One press. We do the rest.

  1. A CV for this posting

    Written against vrtx's own wording, from every piece of relevant proof in your profile.

  2. 25 readers review it

    Recruiter, hiring manager, skeptic and more read every draft, round after round. You get the best round.

    The review screen in CV Rocket: how each CV was read, round by round.

  3. We apply on vrtx's form

    Our application engine gets through the hardest forms there are. Where a question needs you, AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

    An application in CV Rocket: every answer filled in on the employer's form.

  4. Every reply, sorted

    vrtx's answer lands in your private mailbox, and we classify it on arrival: interview, question, rejection.

    The CV Rocket inbox: each employer reply classified as an interview, an action or a rejection.

  5. Reply with AI

    AI helps you write the email, checks it and sends it. We show you whether the recruiter read it.

  6. The interview in your calendar

    Full integration with your calendar. The invitation goes straight in.

    An interview invitation in the CV Rocket inbox, added to the candidate's calendar.
Get the CV for this job

From $25 per CV, paid once. No subscription.

Why it works

3×

more interviews than doing it yourself with ChatGPT.

ChatGPT writes a CV and never learns what happened to it. We see every reply. For each CV we know:

  • How it was written, and how the review scored it
  • When we applied, and how long after the posting went up
  • Which posting, which company, which city
  • Who got the interview, and who heard nothing

That is how we know which CVs get called.

Get the CV for this job

From $25 per CV, paid once. No subscription.

The numbers game

More applications. More interviews.

Every application goes out with its own CV, written for that posting and paid once. Send enough of them and the law of large numbers finds you the job.

Get the CV for this job
By hand5–10
With CV Rocket100
applications a day

Nearby

Live postings like this one

Same employer first, then the same role elsewhere.

Before you press

Straight answers

Get the CV for this job

From $25 per CV, paid once. No subscription.

What if my background isn't good enough?

We make the most of the background you have. The CV uses every piece of relevant proof your profile holds, and one of the 25 readers reads your whole profile and flags what the CV left out.

Do you really apply for me?

Yes, on the employer's own form, the hardest ones included. Where a question needs you, you answer it right there and AI suggests the best answer. Don't want us applying from our IP addresses? Use our Chrome extension: we apply straight from your own browser.

Is it a subscription?

No. You pay once per CV, from $25. Every application goes out with its own CV, written for that posting.

One job. One CV.
Paid once.

Pick the posting you want. We write for it, apply for you and catch the reply.

Get the CV for this job

From $25 per CV, paid once. No subscription.