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Open nowPosted 122 days ago

Senior R&D Scientist - Inhalation Development

Workable (global search)108,016 open roles

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Giza, El Omraniya, Egypt
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Your applicationOpen nowSenior R&D Scientist - Inhalation DevelopmentWorkable (global search) · Giza, El Omraniya, Egypt
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This job: posted 122 days ago

Workable (global search) median: 7 days open

The posting

EVA Pharma is hiring Senior Scientist for the inhalation development team. The role will be responsible for hands-on formulation development, analytical characterisation, scale-up, and process validation of Generic Dry Powder Inhaler products — including capsule-based, blister-based, reservoir-based, dual capsule/blister inhalers, and generic nebulizers.

The role requires deep technical expertise in powder engineering and inhalation science, with the ability to independently drive development activities.

Key responsibilities:

DPI Formulation Development

  • Design and optimise DPI, MDI & Nebulizer formulations for capsule-based, blister-based, reservoir-based, and dual capsule/blister inhalers
  • Develop and evaluate device-formulation compatibility across all inhalation platform types
  • Apply particle engineering techniques — micronization, spray drying, powder blending — to achieve target aerodynamic profiles
  • Develop generic nebulizer formulations alongside DPI programmes
  • Execute feasibility, prototype, and optimisation studies with full scientific documentation

Analytical Characterisation

  • Perform aerodynamic characterisation using NGI and DUSA for in-process and release testing
  • Apply laser diffraction and other particle sizing tools to characterise powder properties
  • Execute and interpret analytical data to guide formulation decisions and device selection
  • Support development and qualification of analytical methods specific to inhalation products

Scale-Up & Process Validation

  • Lead scale-up activities from lab to pilot and commercial manufacturing scale
  • Define and optimise critical process parameters using QbD principles, DoE, and FMEA
  • Execute process validation protocols and compile validation reports
  • Identify and mitigate technical risks through the development lifecycle

Tech Transfer to Manufacturing

  • Prepare technology transfer packages including formulation, process, and analytical documentation
  • Support on-site transfer activities at manufacturing scale and resolve technical deviations
  • Collaborate with production and engineering teams to ensure successful handover

Bioequivalence Support

  • Contribute to bioequivalence protocol design for generic DPI products versus reference innovators
  • Prepare formulation and device rationale sections required for BE study initiation
  • Support interpretation of BE data from a formulation science perspective

Scientific Guidance

  • Provide day-to-day technical guidance to 1–3 junior researchers working on DPI projects
  • Review experimental data, troubleshoot issues, and validate scientific conclusions
  • Maintain up-to-date knowledge of inhalation science, device technologies, and industry trends

Requirements

Education:

PhD or Master's degree in Pharmaceutics, Pharmaceutical Sciences, or related field

Overall Experience:

8–10 years of hands-on experience in DPI development within the pharmaceutical industry

Technical skills:

  • Proven formulation experience across capsule-based, blister-based, reservoir-based, and dual DPI formats
  • Hands-on expertise with NGI, DUSA, and laser diffraction for aerodynamic characterisation
  • Particle engineering skills: micronization, spray drying, and powder blending
  • Scale-up and process validation experience for inhalation products
  • Experience preparing technology transfer documentation for manufacturing handover
  • Contribution to BE protocol design or study initiation for generic DPI products
  • Familiarity with QbD, DoE, and FMEA-based risk management
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