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Open nowPosted 8 days ago

ADME & DMPK SENIOR SCIENTIST

almirall53 open roles

Where
SANT FELIU DE LLOBREGAT
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Your applicationOpen nowADME & DMPK SENIOR SCIENTISTalmirall · SANT FELIU DE LLOBREGAT

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The clock on this job

Early applications get read.

12.7% of postings close within 7 days. Measured by our own scanner across the market. almirall postings stay open a median of 14 days.

Share of postings closed within
  1. 2.2%1 day
  2. 4.5%3 days
  3. 12.7%7 days
  4. 20.4%14 days
  5. 35.6%30 days
  6. 58.7%60 days
This job: posted 8 days ago

almirall median: 14 days open

The posting

We’re building the future of medical dermatology by focusing on unmet patient needs and giving people the space to think independently, take ownership and make an impact that matters.

Our purpose is simple: to transform patients’ lives by addressing real needs. We work with care, act with courage, keep things simple and focus our innovation where it makes a difference.

Recognised as a Top Employer in Spain since 2008 and in Germany since 2025, we continue to invest in an environment where people can grow and move forward.

If you care differently, you belong here.

MISSION

An ADME&DMPK Senior Scientist plays a key role in Almirall’s R&D organization by leading scientific investigations and contributing to the development of innovative therapeutic solutions. In this position a senior scientist will be a member of R&D project teams to provide ADME & DMPK guidance across the non-clinical and clinical development of NBEs, including new drug modalities such as mRNA LNPs, in a multidisciplinary environment.

CORE RESPONSIBILITIES

  • Represent the function in cross-functional teams or in collaboration with external partners, to deliver data and drive informed decision-making aligned with project goals. Ensure that the proper flow of information between the project, the function, and key stakeholders is in place.
  • Participation, performance, direction or outsourcing of studies to improve the knowledge of ADME/DMPK across non-clinical & clinical development.
  • Responsible for the bioanalytical needs (e.g. PK, ADA, Nab or biomarker assays) to support non-GLP or GLP ADME/DMPK studies across drug development, as well as ensure adherence to global regulatory standards (e.g., FDA, EMA).
  • Contribute to the design of pre-clinical and clinical translational strategies and MIDD approaches in collaboration with non-clinical and clinical departments.
  • Ensure that PK, PK/PD, dose predictions or other related non-clinical or clinical PK deliverables are undertaken to best practice standard for study design and regulatory submissions.
  • Provide high-quality data and presentations, both internally and to potential partners, to ensure regular progress updates on ongoing projects.
  • Author high-quality reports, including support to regulatory documents, such as INDs, CTAs, MAA of BLA filings when needed.
  • Evaluate external assets (DDs) for nonclinical and clinical ADME/DMPK, and clearly communicate findings and recommendations to stakeholders.
  • Maintain an up-to-date knowledge of the relevant scientific literature as well as regulatory guidance and best practice.

REQUIRED EDUCATION AND EXPERIENCE

  • MSc/PhD in Pharmacy, Chemistry, Biochemistry, Biology, biomedicine or related Life Sciences.
  • 5+ years of experience in the field of ADME/DMPK/Bioanalysis of Biologic Drugs. Experience with mRNA LNPs and NCE projects will be valued.
  • Good knowledge of the regulatory bioanalytical aspects for biotherapeutics, including clinical immunogenicity activities during development.
  • Good understanding of translational medicine aspects to connect Preclinical/Clinical ADME&DMPK, which includes adequate knowledge of Modelling&Simulation concepts.
  • Comprehensive knowledge of regulatory requirements and guidelines related to ADME/DMPK, enabling effective de-risking of regulatory submissions.

PREFERRED SKILLS AND COMPETENCIES

  • Strong analytical and critical thinking skills.
  • Ability to work independently and in cross-functional teams.
  • Excellent communication and scientific writing abilities.
  • Fluent in both oral and written English
  • Strategic thinker and ability to build and maintain professional networks to support collaborative efforts.
  • Collaborative team player who values diverse perspectives and supports collective success.
  • Demonstrates ownership, accountability, and the courage to challenge the status quo.
  • Results-oriented and agile, able to simplify complexity and make effective decisions.
  • Excellent inter-cultural understanding.

OUR VALUES

  • Care: we listen & empathize, we value diverse perspectives & backgrounds and we help each other succeed.
  • Courage: we challenge the status quo, we take full ownership and we learn from our success & failures.
  • Innovation: we put the patient and customer at the center, we create novel solutions and we empower entrepreneurial mindsets.
  • Simplicity: we act decisively and avoid over-analysis, we understand why before we act and we are agile & keep things simple.
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