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Open nowPosted today

Head of Pharmacometrics

zealandpharma20 open roles

Where
Søborg, Denmark
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Your applicationOpen nowHead of Pharmacometricszealandpharma · Søborg, Denmark

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The clock on this job

Early applications get read.

13.8% of postings close within 7 days. Measured by our own scanner across the market. zealandpharma postings stay open a median of 18 days.

Share of postings closed within
  1. 2.2%1 day
  2. 4.7%3 days
  3. 13.8%7 days
  4. 22.3%14 days
  5. 37.8%30 days
  6. 59.0%60 days
This job: posted today

zealandpharma median: 18 days open

The posting

Does it excite you to build a pharmacometrics function from the ground up, and do you have experience making model-informed drug development the way decisions get made? If this sounds like you, and you are ready to take on a broad area of responsibilities, then you could be our new colleague.

Your new position

As Head of Pharmacometrics, you will establish and lead pharmacometrics as a standalone, strategic capability within Medical & Science in Development & Manufacturing Sciences. You will be the key leader for implementing model-informed drug development (MIDD) as the operating principle of our development organization. The role owns the quantitative basis for dose selection, study design and candidate progression across the portfolio, with a focus on early clinical development. This is a founding role with the mandate to define the function, set the standards and recruit the team.

We offer exciting responsibilities:

  • Define and lead the MIDD strategy and roadmap, including which decisions must be model-informed at each toll gate
  • Embed quantitative decision frameworks into the development process, project team deliverables and governance decisions
  • Design model-informed studies and provide quantitative input to candidate selection and early go/no-go decisions
  • Lead back-translation of clinical data to research, including model-based meta-analyses, and predict first-in-human doses
  • Deliver exposure-response and population PK/PD modelling for dose confirmation, health authority interactions and submissions
  • Build the function by setting modelling standards, defining the sourcing model, managing external vendors and recruiting the team

Your profile

You are a scientifically rigorous builder who is energized by creating something new and operates comfortably with ambiguity. You can translate complex modelling into clear recommendations for senior decision-makers, and you lead change by influencing how an organization makes decisions, not only how models are built. You collaborate easily across sites, time zones and partner organizations, and you take ownership and act boldly.

  • PhD, PharmD or equivalent in pharmacometrics, clinical pharmacology, pharmaceutical sciences or a related quantitative discipline
  • Extensive pharmacometrics experience in pharma or biotech, including leadership of people or a function
  • Demonstrated experience implementing or substantially advancing MIDD within an organization, not only applying it to individual programs
  • Track record in early clinical development, including preclinical-to-clinical translation, first-in-human dose prediction and Phase 1/2 dose selection
  • Experience supporting late-stage decisions and health authority interactions, including authorship of regulatory modelling documentation
  • Expertise in population modelling, exposure-response and simulation tools (e.g. NONMEM, R, Monolix or equivalent); experience in cardiometabolic, obesity or peptide drug development is an advantage

Your new team

You will report to the SVP, Medical & Science, and join the Medical & Science leadership team within Development & Manufacturing Sciences. As the founding leader of a new unit, you will start without direct reports and build the team as the function grows. You will work closely with Clinical Pharmacology, Translational Medicine, Medical, Biostatistics, Regulatory Affairs, Discovery Research and Patient Safety. The portfolio spans a Phase 3 obesity program co-developed with a global partner and a growing early-stage pipeline moving into the clinic.

Let's bond and be bold

We have a unique culture, characterized by excellent teamwork and strong engagement across the organization. And we want you to help us strengthen this culture.

Making bonds is at the core of everything we do. From discovering and developing the best new peptide drugs for patients, to engaging with our partners or connecting with each other. We bond through curiosity and playfulness as a team, allowing ourselves to challenge common thinking and drive future innovation. Join us and let's bond and be bold.

Interested in bonding with us? Then please apply no later than November 25, 2026, or as soon as possible. The applications will be reviewed as they come in. While a cover letter is not required, please include a few sentences in your CV explaining your motivation for applying.

For further information, please contact Talent Acquisition Partner, Caroline Nedergaard; [email protected].

We are committed to an inclusive recruitment process and welcome applications from all job applicants.

About Zealand Pharma A/S

Zealand Pharma A/S (Nasdaq: ZEAL) is a biotechnology company focused on advancing medicines for obesity and metabolic health. Combining more than 25 years of peptide R&D expertise with a proprietary data platform that leverages advanced data-driven and AI/ML approaches, Zealand Pharma aims to lead a new era in obesity and metabolic health. To date, more than ten Zealand Pharma-invented drug candidates have entered clinical development, of which two products have reached the market and three candidates are in late-stage development. The Company has collaborations with global pharmaceutical and biotechnology partners for research, development, and commercialization. Founded in 1998, Zealand Pharma is headquartered in Copenhagen, Denmark, with a U.S. presence in Boston, Massachusetts. Learn more at www.zealandpharma.com.

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