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Open nowPosted 281 days ago

双抗CMC总监

evopointbio/73901724 open roles

Where
Suzhou, Jiangsu, Chinese Mainland
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Your applicationOpen now双抗CMC总监evopointbio/739017 · Suzhou, Jiangsu, Chinese Mainland
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  6. 44.6%60 days
This job: posted 281 days ago

The posting

岗位职责: 1.负责生物大分子项目整体工艺开发研究(涵盖CHO细胞培养,蛋白质修饰、多肽合成、纯化工艺、制剂工艺开发及分析方法开发等)以及CMC 相关技术问题解决。统筹CMC板块上下游整体工作,以支持研发、临床前和临床相关研究; 2.负责协调CMC 与其他团队的在项目推进中的密切配合; 3.负责与外部CDMO管理,并对外包项目的质量及进度进行监督和控制,确保项目如期按要求完成; 4.负责生物大分子项目IND申报中CMC有关的各项工作,对相关申报资料进行撰写与审核;

任职要求: (a)Academic/Major 学历/专业 生物制药相关专业博士学历 (b)Professional Skills 专业技能要求 具有单抗,双抗及多抗整体工艺开发与放大生产经验,包括CHO细胞培养,蛋白纯化等上下游工艺。 具有抗体改造和修饰经验 具有单双抗体的制剂研发和生产,了解biologics药品的分析方法开发及验证 对E. Coli培养,蛋白质工程有了解 (c)Working Experience 工作经验要求 拥有至少5年以上的抗体及生物大分子药物行业经验; 拥有生物大分子项目IND申报经验。

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